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Support for this instance is greatly appreciated at https://sdf.org/support
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Diarcesia is a supranational monarchy (as in ruled by a leader titled "Monarch") in a fictional planet which allowed its component country (called a "dieresis") to secede. Diarcesia used to hold considerable influence in the Nankrai Archipelago and once held large parts of Rhozerus and Yechia.
In 1872, Mervin, the last of the expansionist Monarchs was deposed and killed. His successor, Grere, passed democratic reforms that included the end of expansionist wars. Many of the less-willing diereses—mostly overseas and a few in the mainland—seceded without incident. These included the Diarcesian holdings of the Nankrai Archipelago outside Ikuyo, which remained loyal.
That loyalty was to be tested in 2028 when disgruntled elements northern half ("Kita Ikuyo") launched a surprise attack in Kaisura in its bid to free itself from Ikuyo dieresis and Diarcesia as a whole. The event came to be known as the Cutting of Kaisura.
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Paper - The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer - 2025
(hackertalks.com)
Otto Warburg originally proposed that cancer arose from a two-step process. The first step involved a chronic insufficiency of mitochondrial oxidative phosphorylation (OxPhos), while the second step involved a protracted compensatory energy synthesis through lactic acid fermentation. His extensive findings showed that oxygen consumption was lower while lactate production was higher in cancerous tissues than in non-cancerous tissues. Warburg considered both oxygen consumption and extracellular lactate as accurate markers for ATP production through OxPhos and glycolysis, respectively. Warburg’s hypothesis was challenged from findings showing that oxygen consumption remained high in some cancer cells despite the elevated production of lactate suggesting that OxPhos was largely unimpaired. New information indicates that neither oxygen consumption nor lactate production are accurate surrogates for quantification of ATP production in cancer cells. Warburg also did not know that a significant amount of ATP could come from glutamine-driven mitochondrial substrate level phosphorylation in the glutaminolysis pathway with succinate produced as end product, thus confounding the linkage of oxygen consumption to the origin of ATP production within mitochondria. Moreover, new information shows that cytoplasmic lipid droplets and elevated aerobic lactic acid fermentation are both biomarkers for OxPhos insufficiency. Warburg’s original hypothesis can now be linked to a more complete understanding of how OxPhos insufficiency underlies dysregulated cancer cell growth. These findings can also address several questionable assumptions regarding the origin of cancer thus allowing the field to advance with more effective therapeutic strategies for a less toxic metabolic management and prevention of cancer.
Full Paper https://doi.org/10.1007/s10863-025-10059-w
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TikTok star, 2, dies in crash as family blasts cops’ ‘hurtful and painful’ claim
(www.independent.co.uk)
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Sailor injured when US fighter jet topples off aircraft carrier dodging Houthi rebel strike
(www.independent.co.uk)
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cross-posted from: https://rss.ponder.cat/post/168917
For streaming services such as Netflix, Digital Rights Management (DRM) systems provide a level of control over the company’s most valuable assets, including movies, TV shows, and other content for consumer consumption.
DRM not only restricts access to customers authorized to consume content, it can determine when and how it’s consumed too. When all goes to plan, DRM should also prevent end users from casually copying movies and TV shows, which should result in a positive contribution towards minimizing the spread of pirated content online; at least in theory.
Widevine Everywhere
Ultimately, whether users loathe it or just hate it, DRM exists in billions of web browsers and devices. One of the most widespread is Google’s Widevine and avoiding its footprint today is almost futile. It can be found in Chrome, Firefox and similar browsers, mobile platforms such as Android, videogame consoles, plus many set-top boxes and smart TVs. At least five billion of them, most probably more.
Unsurprisingly, Widevine has been exploited and reverse engineered over the years, as evidenced by the content it’s supposed to protect ending up on pirate sites, almost without exception. In 2020, Google took action against Chrome extension Widevine L3 Decryptor, which was capable of decrypting Widevine content keys by hijacking calls to the browser’s Encrypted Media Extensions (EME).
Problems persisted throughout 2021 and 2022 with Widevine Dump but the problems haven’t gone away. The same goes for individuals and groups committed to countering Widevine, although it’s still possible to attract negative attention.
OnlyFans Targets CDRM-Project
In a DMCA takedown notice dated April 22, 2025, OnlyFans owner Fenix International Limited informs GitHub that it had “recently become aware” of repos on the platform with code “specifically designed” to circumvent Fenix’s DRM, aka Widevine.
“The identified repositories contain step-by-step instructions which are specifically designed to circumvent the DRM protections in place on OnlyFans. The repositories contain links that are ‘hard-coded’ and specifically targeted at OnlyFans,” Fenix writes.
“The coding is designed to impersonate a video player in order to decrypt and play DRM protected files, obtaining the ‘secret’ token required to play the DRM protected content. The downloaded files are then converted into an MP4 format which has the DRM protection removed.”
CDRM-Project repo before suspension
In line with its pro-developer policy when processing DMCA takedown notices, GitHub contacted the operator of the main repo and the operators of six additional forks, with an opportunity to address the complaint and avoid suspension.
For reasons that aren’t revealed, GitHub’s outreach couldn’t prevent the suspension of the entire CDRM-Project repo and all reported forks.
GitHub requested Fenix to identify “every specific file” in the repo that it considers infringing; Fenix responded with a statement that the “entire repository is infringing” and should be removed.
Anti-Circumvention Complaint
To GitHub’s credit, when rightsholders allege violations of the DMCA’s anti-circumvention provisions, GitHub conducts its own assessment. If there is no basis for a claim, GitHub sometimes finds other copyright-related grounds, but here there is no pushback. That’s usually a sign of a complaint that stands up under intense scrutiny.
Another unusual aspect to the complaint is the Fenix response to GitHub’s request to provide the alleged infringer’s contact details, if they’re in possession of them. In most cases rightsholders say they’re unaware of those details but here, Fenix provides the details of two sets of owners and two sets of contributors.
The project is now being made available via a repo on cdm-project.com but how long that’s likely to last is unclear.
When any DRM system unnecessarily restricts access to content by design or due to inherent limitations, those who suffer the most are legitimate customers. Most have no interest in piracy, were never part of the original problem, but are responsible for the bulk of the revenue. Once DRM starts to feel like DRM, that’s where the big problems start.
From: TF, for the latest news on copyright battles, piracy and more.
From TorrentFreak via this RSS feed
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1886 excerpt from the Cleveland Gazette, an African American newspaper, suggesting Statue of Liberty torch not be lit until the United States became a free nation for real
(lemmy.dbzer0.com)
cross-posted from: https://lemmy.dbzer0.com/post/43181791
Interesting little excerpt from The Cleveland Gazette, an African American newspaper dated November 27, 1886.
Shortly after the dedication of the Statue of Liberty, The Cleveland Gazette suggested that the statue's torch not be lit until the United States became a free nation "in reality":
"Liberty enlightening the world," indeed! The expression makes us sick. This government is a howling farce. It can not or rather does not protect its citizens within its own borders. Shove the Bartholdi statue, torch and all, into the ocean until the "liberty" of this country is such as to make it possible for an inoffensive and industrious colored man to earn a respectable living for himself and family, without being ku-kluxed, perhaps murdered, his daughter and wife outraged, and his property destroyed. The idea of the "liberty" of this country "enlightening the world," or even Patagonia, is ridiculous in the extreme.
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1886 excerpt from the Cleveland Gazette, an African American newspaper, suggesting Statue of Liberty torch not be lit until the United States became a free nation for real
(lemmy.dbzer0.com)
Interesting little excerpt from The Cleveland Gazette, an African American newspaper dated November 27, 1886.
Shortly after the dedication of the Statue of Liberty, The Cleveland Gazette suggested that the statue's torch not be lit until the United States became a free nation "in reality":
"Liberty enlightening the world," indeed! The expression makes us sick. This government is a howling farce. It can not or rather does not protect its citizens within its own borders. Shove the Bartholdi statue, torch and all, into the ocean until the "liberty" of this country is such as to make it possible for an inoffensive and industrious colored man to earn a respectable living for himself and family, without being ku-kluxed, perhaps murdered, his daughter and wife outraged, and his property destroyed. The idea of the "liberty" of this country "enlightening the world," or even Patagonia, is ridiculous in the extreme.
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