PineNote (Pine 64) or reMarkable (Pro if you have budget, 2 or even 1 otherwise)
Both work on Linux proper, the reMarkable comes with Linux out of the box whereas PineNote comes with Android but one can install Linux on it.
They are mostly to sketch but it is also good to read. You can pretty much use whatever you want on them, including developing your own software. I don't know if they have Calibre clients because whats I do is... just scp
my ePubs or PDFs on there.
Here are my tinkering notes on both https://fabien.benetou.fr/Tools/Eink but feel free to ask any clarification.
PS: the Bookeen Diva also does not require any software, namely you can plug it on Linux, it gets detected as a filesystem and you can copy DRM-free content on it. It's a totally different form factor (much smaller so IMHO not great for comics) and I don't think there is the same open-source community as the other 2.