... trying to view the whole universe as a big simulation ...

Ding ding ding! We got another simulation hypothesis techbro! All who got bingo raise your hands. Everyone else, better luck next time.

If you're trying to embed physics into computation, it's very natural for you to embed AI into the physics of the world.

I can't tell what this is supposed to mean even viewing it through rose-tinted tech optimism goggles. Embed physics into computation? Bro, that's called "electricity". Embed AI into physics? OK now you've completely lost me.

[noise is] also a problem if you're trying to go low power on [illegible] computers, and so what these devices do they use the noise from heat-- the jitteryness of the elctrons-- as an asset rather than a liability.

But seriously what the hedge is he talking about?

It's just some vague buzzwords about using ~~quantum computing~~ (edit: not quantum, based on the follow up video) to ~~embed intelligence into the universe in the most efficient way possible~~ solve unspecified classes of machine learning problems.