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this post was submitted on 23 Oct 2024
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Migraine
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I've had good experience using psilocybin mushrooms. Do what you want with this information Here is a journal from
University of Toronto
The authors’ research group recently reported on the preventive or transitional effects of a pulse regimen of low-dose psilocybin (10 mg/70 kg) for cluster headache in a randomized, double-blind, placebo-controlled trial.31 The dose (mildly psychedelic) and regimen (3 doses, each 5 days apart) were based on those used by patients.5 In the study, psilocybin reduced cluster attacks per week by approximately 30% over three weeks, although this reduction did not reach statistical significance against placebo (p = 0.251; n = 14).31 A Danish group also reported on the effects of the same pulse regimen for cluster headache and included measures of brain functional MRI.32 In this open-label investigation, there was an approximately 30% reduction in attack frequency in the four weeks after pulse completion (p = 0.003; n = 10), which correlated with hypothalamic functional connectivity changes after psilocybin.32 The hypothalamus is a key brain region in the pathophysiology of cluster headacheThat sounds very interesting! I am already on a new med so I might have to wait to try something like that (I am on a CGRP targetting med now) but it sounds promising. What was your experience with it?
I get really high for a night and next 6-12 months 0 headaches. I take em when I really need em. Same goes for depression, feel fantastic for a couple weeks after