a reddit user shared their story
Just woke up to an Email from PayPal stating that my account was permanently limited, thinking it's a scam I check and lo and behold: I was limited.
But what had I done? Well my only purchases using PayPal were through Itch.io, that's the only thing I use it for.
It seems I was limited for breaking "the policies of our partners" mentioned in the first paragraph of the notice. It's no secret that PayPal are quite close with Mastercard and Visa, who have been pushing hardest for this porn ban (sorry, specifically the NSFW Games sphere).
So this is a PSA: if you're using your PayPal account for anything else, don't use it for Itch.
A quick search of the phrase brings up more the "make sure the science done is credible and that you did not massage your data to end up with a specific result" type of skepticism, but I'm guessing the person you replied to meant the type of person who says vaccines do not work and they are just skeptical of all this science stuff in general.