BG3 has events where you can't sleep or they complete without you.

Waukeen's rest burning is the first one that comes to mind. If you stumble on it and then rest, Counselor Florrick will die. You have to complete it when you get to it. In a similar vein if you travel to the mountain pass before saving Halsin he will die in the goblin camp. I think that's because multiple days pass in the story when you go the mountain pass route instead of the underdark route.