Plague Tale (Both games are solid, but 2 was sooooo good)

Rakuen was the most recent game I played that did that for me

It was short and sweet but Planet of Lana got me in the feels a little bit.

Tales, Xenogears

Rime is hauntingly beautiful in a way that hits you as it finishes.

Telltale Games Walking Dead. Not a game, but a whole series.

That Dragon, Cancer. Part game, part visual novel.

Death Stranding

Papers, Please. Maybe not crying, but could definitely put you into a depressed mood if you manage to get into character. Needing to make a choice between letting some poor bastard's wife follow him without proper papers and feeding your family is tough.

Had a quick scroll through and didn't see it anywhere yet, so:

Dear Esther.

Actually, reminds me I should play through it again, it's been a few years.

Titanfall 2... Goodness that ending had my kiddo misty eyed. As for me, there was dust in my hand room or my allergies were acting up.

Mother 3 got me tearing up when I first played it

Persona 4 Golden is a beautiful game that made me emotional more than once.

Portal 2. But you should play the first part before sequel, if you haven't already.

Haven't actually played it yet but a video about MOTHER 3 made me cry just talking about the story (not only that but the part where he talked about the story made me a little emotional)

Here is the video btw

You may already know it but Omori was heavily inspired by the mother series and especially Mother 3: https://twitter.com/_omocat/status/1384687971929006080