Meh. I run proxmox and other boot drives on ext4, data drives on xfs. I don't have any need for additional features in btrfs. Shrinking would be nice, so maybe someday I'll use ext4 for data too.
I started with zfs instead of RAID, but I found I spent way too much time trying to manage RAM and tuning it, whereas I could just configure RAID 10 once and be done with it. The performance differences are insignificant, since most of the work it does happens in the background.
You can benchmark them if you care about performance. You can find plenty of discussion by googling "ext vs xfs vs btrfs" or whichever ones you're considering. They haven't changed that much in the past few years.