But wouldn’t a huge plane be able to absorb those volume losses by having more volume in general?
In theory, yes, I suppose so, but in reality you'd need to do the math to get an answer to your question. The thing here is "huge" is a relative statement. Does "huge" mean 747 sized? Or does it mean 4x 747 size? Because something that large is likely not practical for reasons aside from hydrogen practicalities.
Assuming it were possible to work through the engineering of such a plane, you'd also need to completely rebuild airports to account for something that big (see the 777X with folding wingtips to avoid the problem of needing wider gates). That said, I'm sure someone has already done this analysis and came to an unfavorable conclusion because if it checked out Boeing and Airbus would be racing to have hydrogen airliners ready to go in the not too distant future.