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Neuroscience AMA (sh.itjust.works)
submitted 9 months ago by zsnell02@sh.itjust.works to c/neuro@lemmy.world

Hey all, I’m a neuroscience grad student bored as hell while working on research, AMA

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[-] jeffhykin@lemm.ee 4 points 9 months ago

What kind of grad program are you in where you're bored as hell?? I've never met a grad student with any kind of free time

[-] zsnell02@sh.itjust.works 2 points 9 months ago

I'm in the +1 portion of my 4+1 program. We're researching how attention and sensory input changes time perception, which includes our participant sitting in room doing nothing for an hour as a baseline, so we get more downtime than we'd like sometimes lmao.

[-] Candelestine@lemmy.world 2 points 9 months ago* (last edited 9 months ago)

In the brain, we seem to have numerous analog chemical systems that kinda operate alongside our binary on/off neurons. Things like hormone levels, that can create a shift in how other interactions play out across the system as a whole, in a sliding gradient as opposed simple on/off.

Roughly how many of these (edit: central-)nervous-system-wide analog communication systems are there?

[-] zsnell02@sh.itjust.works 2 points 9 months ago

That’s a hard question because of the interconnected-ness and complexity of the systems but I’ll give it a shot.

Neurotransmitters: ~30 Neuromodulators: ~10-20 (some transmitters also act as modulators) Hormones: 10 Growth Factors: ~5 Endocannabinoids: 2 Gaseous Neurotransmitters: 2 Peptides: ~30 Ion concentrations: ~5

So all that together I want to say there’s about 100 or so distinct “analog” signaling systems, but a lot of these molecules can function in multiple capacities, like neurotransmitters can act as neuromodulators and etc.

[-] Candelestine@lemmy.world 2 points 9 months ago

Thank you, that is exactly the kind of ballpark answer I was looking for. That's honestly less than I was expecting, I can actually wrap my head around 100ish chemical signaling systems.

this post was submitted on 28 Sep 2023
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