In most cases, “life-threatening side effects” would be a dealbreaker for me. But if I have a mentally degenerating illness when I reach that age, I’d absolutely be in the “let’s fix it or let me die” camp. Either would be preferable to going through the motions of life while forgetting everything and everyone.

my grandfather had alzheimer's. dying from a side effect would have been better than the last 2 years of his life

Sounds good but:

Dr. Alberto Espay, a neurologist at the University of Cincinnati College of Medicine, said that the 27% slowing in the progression of the illness falls below the threshold of what would be "noticeable" to a patient.

“The odds for brain swelling and hemorrhage are far higher than any actual improvement,” said Espay, who launched a petition in June calling for the Alzheimer’s treatment to not get full approval.