I have a USB-C hub that has an NVMe slot built in and offers USB-PD power passthrough. My intention had been to use that hub to dual boot Windows from a 2TB NVMe so I could run native Gamepass and Genshin Impact on my Steam Deck, while keeping the majority of that drive formatted to share games between SteamOS and Windows, but it seems that any time the device changes power states the NVMe drive is disconnected and reconnected as part of the process.
This is problematic enough when I start Windows from the NVMe SSD in the enclosure connected to power, things work fine until the Steam Deck reaches full charge and the USB-PD is renegotiated so as to run things from the charger rather than continually topping up the battery. Windows dies immediately because the disk briefly goes away and comes right back. So fine, I just don't start my Deck with the hub connected unless the Steam Deck is fully topped off and problem solved?
That's all fine and well, but it becomes unbearable when I use my fancy 120w charging brick that offers multiple USB ports to power/charge multiple devices which charger renegotiates every device plugged in whenever any device is added, removed, or changes power states. If my Kindle Fire hits full charge while I'm playing on my deck, the connection to the NVMe storage is killed and anything with files open from the drive takes a dump. This happens in Windows and in SteamOS.
I've used the same NVMe drive in several different external enclosures hooked up via USB-A, with several different USB chargers (all 65w or higher,) all through the same hub that has the NVMe slot built in, through a fancier Lenovo hub, and a through a cheap $20 number from Amazon; all of the hubs have USB-PD passthrough and no matter what the setup it seems like no drive will stay connected in any arrangement if the power delivery situation changes in any way.
The question then is this: What is responsible for this behavior?
Is the Steam Deck uniquely unable to keep data connections open while power delivery is renegotiated, are all 3 of the hubs I have botching things and another hub would allow this behavior I desire, or is this normal for the USB spec and it's just not possible to have a reliable data connection going during a USB-PD state change? I've been unable to find any answers searching the Internet, so if you've got an authoritative source on the answer to my question, I'd love to see it and know if I should just give up on my dream or if there's a solution somewhere.
So this is neat. Potentially life changing for some type 2 diabetics, but that depends because some t2 diabetics are not failing to make enough insulin, they're just no longer sensitive to it at a level that makes it functional for them. I suppose it's possible that this therapy could cause them to grow enough islet β cells to overcome their lack of sensitivity, but (and I'm a type 1, not a type 2, so maybe my info is incorrect here) that lack of sensitivity can grow with further exposure to insulin making this a stop-gap at best for those cases absent other therapies.
...and with all of that said, being able to regrow islet β cells has never really been the problem for type 1 diabetes. You can regrow all the islet β cells you'd like and it's not going to cure the underlying immune disease that has caused your immune system to kill off all of your islet β cells to begin with. Unless you can figure out why t1 diabetes causes one's own immune system to go psycho killer on their islet β cells, you've done nothing to "cure" diabetes. Without being able to suppress that impulse for your immune system to murder your own cells, any ability to replace the islet β cells is going to be temporary at best, and probably a waste on the whole.
My brother in law is a "cured" type 1 diabetic, by virtue of his having had a kidney replacement and being on immune suppressing drugs for that. Since they were already replacing the kidney and he was going to have to take immune system suppression medications for that, they also just replaced his pancreas at the same time and the suppression of his immune system has allowed the new pancreas to thrive and continue to make insulin. Easy-peasy. The only trade-off is that he is super immunocompromised and can be killed by common colds, so not a great strategy in general.