I'll be honest, I'm from Minnesota but haven't seen TMD. But I love when shows emphasize and feature its location. Even if it wasn't filmed there, The Mary Tyler Moore Show kept things reasonably Minneapolis-centric. Cheers/Frasier in Boston/Seattle, The Drew Carey Show is proudly in Ohio, Seinfeld in New York, Full House in San Francisco, more recently Breaking Bad in New Mexico... We've got a huge country, let's use its different settings!

Unfortunately so many places are lucky to offhandedly mention where it all takes place, trying to appeal to the lowest common denominator IMO.