I recently beat Antimatter Dimensions after coming back to the Reality update after a long while. There's a lot of depth, especially in the new additions. I appreciate all the layers and addition of QoL upgrades.

Bitburner was fun as an incremental hacking sim. I haven't played it for a while, but I find it really unique.

There's also Orb of Creation which can be a bit grindy but also seems really fun for what it offers. I've been playing the demo version at https://marple.itch.io/orb-of-creation