this post was submitted on 06 Jul 2025
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This video discusses cholesterol, its implications on health, and how to interpret cholesterol blood tests, especially in the context of a ketogenic diet.

  • Dr. Paul Mason discusses cholesterol, its types, and how to interpret cholesterol blood tests, emphasizing that high LDL levels aren't always a cause for concern.

  • Cholesterol is often misrepresented; it refers to various lipoproteins that transport fat in the blood, not just the fat itself.

  • LDL is not inherently bad; it can become harmful when damaged by sugar through processes like glycation and oxidation.

  • The presence of small dense LDL particles is associated with increased heart disease risk, primarily due to their damage from high glucose levels.

  • Accurate cholesterol testing can be complicated, as standard tests may not measure all lipoproteins directly, leading to estimations that can affect results.

  • Triglyceride levels and HDL levels can provide insights into whether an individual is likely to have a healthy (pattern A) or unhealthy (pattern B) cholesterol profile.

  • A low triglyceride level (<0.5) and a high HDL level (>1.5) correlate with a healthier cholesterol profile.

  • The Feldman protocol suggests that following a high-fat diet for three days can significantly lower LDL levels by increasing LDL receptor expression.

  • Insulin plays a crucial role in regulating LDL receptor expression; higher insulin levels increase receptor numbers, facilitating LDL removal from circulation.

  • High carbohydrate diets and elevated blood glucose levels contribute to the formation of damaging LDL particles, which are linked to cardiovascular risks.

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[–] jet@hackertalks.com 2 points 2 weeks ago