this post was submitted on 21 Jul 2025
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My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

Can it really be so much different? Both claim to have a 50 % instant-release part.

Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-removedpraeparaten.html

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[–] JuBe@lemmy.world 2 points 9 months ago

A little bit late to the party, but if you're in the U.S., you should report this to the FDA's MedWatch, here. There's some backstory here, but from personal experience, I can say that the different release mechanisms (e.g., osmotic) can have an impact. It sucks.