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[Article] Male Birth Control Pill to Stop Sperm Production Passes Safety Test (www.scientificamerican.com)

submitted 4 days ago by BrikoX@lemmy.zip to c/interestingshare@lemmy.zip

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A hormone-free pill, called YCT-529, that temporarily stops sperm production by blocking a vitamin A metabolite has just concluded its first safety trial in humans, getting a step closer to increasing male contraceptive options

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[–] turdas@suppo.fi 3 points 3 days ago (1 children)

Going several months with blocked vitamin A metabolism sounds like it'd lead to a vitamin deficiency of some kind.

[–] DrWorm@piefed.blahaj.zone 7 points 3 days ago

The daily pill, called YCT-529, blocks a vitamin A metabolite from binding to its receptor in the testes; this action prevents the chain of gene-expression changes that are required to start the sperm-making process.

It’s not supposed to effect the rest of the body, but I assume that’s one the side effects they’d be on the lookout for in this trial