I used CalyxOS on Fairphone (still waiting for the new one) and that was a good experience. I had completely degoogled main profile and then work profile with microG for things that doesn't really work without google services or for apps that I simply needed but didn't want running all the time. And the work profile was off most of the time. It was a good balance for me. Now I am waiting and using LineageOS, but will jump on the CalyxOS bandwagon once they are back. Also prior to CalyxOS I waited for any ROM, I had just pure FairphoneOS (just an android) and honestly, Fairphone should do something about their software because there were a lots of bugs, some were not solved for a long time and when custom ROMs became available, they were better tuned than the FairphoneOS. I mean seriously, good hardware bad software...