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YouTube adds new hurdles for ad blockers, and there's currently no way around it
(www.androidauthority.com)
This is a most excellent place for technology news and articles.
Ublock Lite still works on Chrome. There are no custom filters and it doesn't block a lot of annoyances (like "Sign In With [brand]"), but it gets the job done for most people.
But honestly if you want have the most reliable adblocking experience, then Firefox w/Ublock Origin is still your best bet (also YouTube ReVanced for mobile and SmartTube/SmartTubeNext for TVs).