this post was submitted on 10 Mar 2026
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alright, someone explain to me how this actually sucks and we shouldn't get our hopes up.
It's not a vaccine
It will only work if you expect to catch a virus
Overusing a signaling pathway just turns off receptors
Mouse only.
Well, for one this is a study in mice. It is a long way from becoming a commercial product and might not be translatable between mice and humans.
I am a bit skeptical about the allergen protection since in mouse models the mice are "being made" allergenic during the model duration. That is being blocked it seems. If that also means that if you already have the allergy, this new vaccine would block it going forward, hard to say. If one could vaccinate children with this, they may not develop such allergies though, which would be interesting!
Interesting. Ok, so we're still a decade or so off from this being viable for humans then? And it sounds like it's basically keeping you in a mild state of always having allergies to keep your immune system running on all cylinders, correct? So that might have some long term effects as well?
It's like any other drug that activates receptors, the receptors get burned out and the whole signaling pathway gets shut off.