Quark: I should've listened to my cousin Gaila. He said to me, "Quark, I've got one word for you...weapons." No one ever went broke selling weapons. But did I take his advice? No. And why not? Because I'm a people person. I like interacting with my customers. Like you and I are doing right now. Talking to each other, getting to know one another...

Garak: I can see the attraction...for you.

Quark: But when you're dealing in weapons, buyers aren't interested in casual conversation. They just want their merchandise, no questions asked. It's so impersonal.

Garak: Your charms would be wasted.

Quark: Exactly. So now Gaila owns his own moon, and I'm staring into the abyss. And the worst part is, my only hope for salvation is the Federation.

At least his fortunes seemed to have changed by Lower Decks' time, judging by all the Quark signs everywhere.