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A community for transfeminine people and experiences.

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Some helpful links:

The Gender Dysphoria Bible // In depth explanation of the different types of gender dysphoria.
Trans Voice Help // A community here on blahaj.zone for voice training.
LGBTQ+ Healthcare Directory // A directory of LGBTQ+ accepting Healthcare providers.
Trans Resistance Network // A US-based mutual aid organization to help trans people facing state violence and legal discrimination.
TLDEF's Trans Health Project // Advice about insurance claims for gender affirming healthcare and procedures.
TransLifeLine's ID change Library // A comprehensive guide to changing your name on any US legal document.

Support Hotlines:

The Trevor Project // Web chat, phone call, and text message LGBTQ+ support hotline.
TransLifeLine // A US/Canada LGBTQ+ phone support hotline service. The US line has Spanish support.
LGBT Youthline.ca // A Canadian LGBT hotline support service with phone call and web chat support. (4pm - 9:30pm EST)
988lifeline // A US only Crisis hotline with phone call, text and web chat support. Dedicated staff for LGBTQIA+ youth 24/7 on phone service, 3pm to 2am EST for text and web chat.

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Did Melatonin have any effects on your dysphoria? (lemmy.blahaj.zone)

submitted 1 week ago by feiras@lemmy.blahaj.zone to c/mtf@lemmy.blahaj.zone

6 comments fedilink hide all child comments

So I'm basically doing an autism deep-dive into endocrinology at the moment and I came across this study, which suggests that

There have been good results in recent research to inhibit the generator of pulsatile secretion of GnRH necessary for ovulation by using melatonin in a new type of oral contraceptive.

As far as I understand from this article, GnRH basically stimulates biological hormone production (testosterone & LH in biological men; progesterone and estrogen in biological women).

If melatonin reduces GnRH production to such a level that it may even be used as a contraceptive, I cannot help but wonder, if any of you remember any supplementary (gender affirming) effects if you have taken melatonin before or during replacement hormone therapy?

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[–] ada@lemmy.blahaj.zone 10 points 1 week ago (1 children)

All I remember is that it made me wake up feeling like I was slightly hungover.

[–] oftheair@lemmy.blahaj.zone 1 points 1 week ago (1 children)

If you'd like to say how much did you take?

[–] ada@lemmy.blahaj.zone 2 points 1 week ago (1 children)

I honestly don't remember. It was 5 or so years ago. From memory, they were small brown gel caps, and I initially took 2 of an evening, but moved down to 1, before stopping. Can't remember the dose in each cap

[–] oftheair@lemmy.blahaj.zone 1 points 1 week ago

Thank you!

Yeah, we took too much in vegan gummies (just two) and gosh we were so depressed the next day. We stopped after that.

[–] dandelion@lemmy.blahaj.zone 2 points 1 week ago

no, but melatonin did increase my parasomnias and likelihood of discomfort if I didn't fall asleep quickly enough, so I avoided it pre-transition (I guess I still do, but my parasomnias and nightmares are far less common since I started estrogen).

[–] oftheair@lemmy.blahaj.zone 1 points 1 week ago* (last edited 1 week ago)

If you do take it, take as little as is effective. We took too much at least once and it made us feel depressed. Start small and work your way up a very little at a time if, and only if you need more.