GeneralVincent

I'm not sure that's the best source. I don't see any links to sources for the progesterone claims, and there's a bunch of fear mongering regarding doctors and official medical advice. Like

Don't give a vial into the hands of a doctor, he'd destroy it. Doctors are jealous.

and

Medical professionals routinely make mistakes in both directions: approve crazy people and unnecessarily delay transsexuals who'll not regret.

and

Endos are used to such approach, it keeps them busy and paid. With the only goal to maximize quantity of doctor visits paid by patients or insurance, gangs of American endos write guidelines how to treat transsexuals: with same approach. All the numbers in such guidelines and all the bogeyman stories about side effects of estradiol are bullshit. "Normal range" is from measurements of 90% of healthy people: 5% of lowest and 5% of highest results are discounted. Normal range of estradiol for pregnancy is up to 40000 pg/ml = 147000 pmol/l. In a group of 86 pregnant women estradiol level was up to 75137 pg/ml = 275753 pmol/l: http://cebp.aacrjournals.org/content/12/5/452.figures-only. Pregnant women don't drop dead from such estradiol level, so you wouldn't even if your peak reaches 5000 pg/ml. It's even darker than that: the numbers in guidelines are chosen deliberately low to force transsexuals to pay for more doctor visits to beg for more estradiol. Doctors also recall the mantra in their gospels (textbooks) about estrogens: dosage the less the better, stop as soon as possible. They never realize that this mantra was written in the fear of uterine cancer. And that you haven't an uterus.

I appreciate the link to source here at least, but I think the logic is flawed and not the best advice. I totally get assuaging fears of estradiol overdose, but peak estradiol isn't the same as sustained, long term elevated levels.

Also, saying there's no evidence for low dose methods-

So they claim that it's allegedly better. Doctors in other countries parrot that. There isn't any evidence. People repeat doctors' claims.

-but then advocating for higher dose with no research evidence seems like hypocrisy to me

You're posting propaganda when your statement has no source and is not supported by evidence

19.4% The percentage of Ukrainian land occupied by Russia, according to the Institute for the Study of War. Over the past year, Russia has gained just 0.79% of Ukraine's territory in the grinding war of attrition, the Washington-based think tank said in calculations provided earlier this month to The Associated Press, underscoring the little progress Moscow's forces have made despite huge costs in troops and armor.

Source: https://www.pbs.org/newshour/world/4-years-into-russias-invasion-of-ukraine-a-look-at-the-war-by-the-numbers

Their kingdom is still defending itself incredibly well against the larger nation after four years, with Russia taking extremely heavy loses with no clear sign of victory on either side. The recent fighting has gained barely any ground at all for Russia

What do you think the solution to that problem is?

Yup, I made a bad generalization. My bad, and to be clear I'm not a doctor or anything.

Some SSRIs may have an interaction with grapefruit. But grapefruit interacts with different medications differently, and it's not based on the class of medication, it's med specific.

e.g. Sertraline (Zoloft) is an SSRI and is listed as having an interaction with grapefruit

https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions

Eta: thanks for calling that out, I've learned some interesting things, for example;

Ketamine: After drinking 200 mL of grapefruit juice daily for five days, the overall absorption of orally ingested ketamine was increased three-fold compared to the control group in a clinical trial. The peak blood ketamine concentration was increased over two-fold.

~~No grapefruit while taking ssri medication~~

edit: sorry, this is a bit misleading and an oversimplification

https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions

"Male penguins may exhibit homosexual behavior. However, as the author, I would like to make it clear I would NEVER have gay sex with a male penguin. That's gross. I would only ever have sex with a woman penguin, as Putin would want."

It's not exactly the same but the Clicks phone keyboard is touch sensitive so you can swipe on the keyboard, and the button on the side has a notification LED

Yeah fair enough, didn't mean to sound argumentative

Pretty sure thats the point tho, there are often multiple different explanations for each mystery. So having a diverse group of archeologists is beneficial to get as many theories as possible.

So the 'gotcha' by the professor probs isnt a 'this is definitely the only explanation', it's just to have the students question their biases and seek diverse opinions.

Well not overnight obviously, I'm sure it has to go through a board of directors and have a vote for it. My comment may have come off a bit more flippant then intended tbh. But I'm not aware of any legal reason they can't go that route though, but I'm not in the UK so ¯\(ツ)/¯

I did find this, which I think is relevant. https://the-icm.co.uk/wp-content/uploads/2023/12/CC363.pdf

What legal reasons? They're not legally bound to only accept cis women, its just one of their own rules. They don't have to go through the courts, they can change their bylaws to include trans women. Or whatever verbiage they need.

Unless I'm missing something, they have no legal obligation to keep the same bylaws as an organization. Then there's no basis for a terf to sue.

ETA: whoop, missed this part of the article apparently;

Green said the organisation wanted trans women to remain “part of the WI family” and that from April it would launch new “sisterhood groups”, open to all, which would be “a place where we will recognise transgender women as women and explore what it is to be a woman in the 21st century."

So if that's possible, then it seems absurd that the main organization could be at risk of legal action

Kinda, but the big difference is being a man is an identity and not a choice, while being a cop is entirely an intentional choice.

So we should be empathetic to the perspective and struggles of women while trying not to demonize men as an identity.