You kind of need to watch more towards the end, he spends the early part establishing that she was not all bad(to make it look like he isn't just a hater).

His complete argument is not that she is "anti-establishment" but rather that she is consciously doing:

1- (20:00) Bad YT clickbait that panders to both science enthusiasts and science deniers. No matter our opinion on capitalism(consumerism etc) when chud flat earthers start quoting you that is bad yeah? She doesn't make specific arguments and rather just resorts to grandiose statements on how all of science now sucks and she doesn't even make arguments but just rants based on shit using tactics. like throwing a bunch of science terms people don't understand to make her sound convincing.

2- Sabine is embarrassing herself and the entire scientific community by generalizing her tiny field of experience and anecdote into making grand claims about things she literaly knows nothing about.

Here she is literaly science woman does big Dunning Kruger shit.

(23:00)For example the best example is she went on a hilarious rant that scientists were fabricating theories and evidence akin to biologists fabricating fictional animal species 200 years ago. She embaresses herself with just how confidently wrong she is given this is very much how we actualy made real progress(Higgs Boson). Particle scientists don't fabricate particles out of nowhere, we actualy make predictions of what particles should exist if our theories are supposed to correct.

She tries to mocks Particle physics by even misunderstandings what "Particle zoo" actualy means.

3-(30:00) In the end she provides nothing of value because she doesn't make specific arguments. She is the old men angry at clowds complaining that back in my day real men did real science.

But the reality is she could make real science educational videos since she is not actualy bad at it. But due to how YT works she is pandering to a large audience of science deniers(including climate deniers) that only care about her YT thumbnails anyway.

She is doing far more harm than good now. The view count on her videos is obvious evidence she is deliberately turning towards and pandering to the science denial viewers and this is not critique or useful at all.