The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
This. Kbinauts should encourage using the block button, rather than demanding defederation. Curate your own experience, don't try to curate others' experience. Please and thank you :)