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I was talking to my hairdresser last week and she loves injections. Guess she forgets enough that pills everyday are too much for her. I'm taking mine in the morning, evening and then progesterone right before bed. So, three times a day I have to take pills. Guess I'm curious what your thoughts about the differences are and if it's just about convenience, as the injections are only once a week, or are there any other benefits one way or the other.

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[-] NoStressyJessie@lemmy.blahaj.zone 10 points 1 year ago

I do injections because I’ve heard it’s easier on your liver (or maybe kidneys I forget exactly ATM). It also has a higher absorption rate, and as a monotherapy I like not having to keep track of multiple medications.

I hated needles prior because of some traumatizing OD deaths in homeless camps (I kinda made it my litmus test to see how much I wanted HRT), but after about 2 weeks my anxiety was gone, and the benefits far outweighed the momentary ick of stabbing myself with a needle.

Monotherapy. I've heard that word used before, are you saying you don't take any blockers? Or progesterone? How's that work?

Yeah, I’m just taking a large enough dose that testosterone is nuked by itself. I can add progesterone later, but I’m early in my medical transition, and have heard it’s better to wait a bit.

I heard if you take too much estrogen your body reverts it back into testosterone and you go backwards. Arg all this is so frustrating sometimes. Sorry. I'm glad to hear this, now I want to know more cause I really dislike spiro. i asked my plume provider about injections but they only gave me onfo on how to inject and how needles work. Not really what I was looking for from them.

Testosterone can convert to estradiol via aromatase, however there's no metabolic pathway in the other direction.

I haven’t heard anything about that, but so far my T seems very well suppressed. Random erections are gone, ejaculate is thinner and clear, breast soreness, nipples have started changing, etc.

Ya it's very possible that info is old, outdated, and wrong. Now I'm really interested. Like I said I really don't like spiro. And ya I didn't start progesterone until after 18 months. I was on super low does though so I didn't even get to an a cup. When I switched to plume a month ago they put me on 100mg prog before bed. I sleep great now it's nice. Feels like I'm felling out a bunch now too.

[-] NoStressyJessie@lemmy.blahaj.zone 4 points 1 year ago* (last edited 1 year ago)

I’m in Florida, wait times are long, prescriptions are expensive, and they can refuse to fill it anyway, so I have had to educate myself with resources such as diyhrt.wiki. My knowledge isn’t necessarily comprehensive.

[-] Entertainmeonly@lemmy.blahaj.zone 2 points 1 year ago* (last edited 1 year ago)

Ya all my knowledge comes second hand as well. So, I'm always asking others that have real world experience with it. Plume was super easy and nice to get my prescription from but I haven't gotten any info from there that was not just surface level. You know?

this post was submitted on 18 Aug 2023
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