I found most failed rolls in DE made me enjoy the moment more, sometimes even moreso than a success. Especially with non-recoverable red checks. The only times I save scummed were when I kept failing a white check I had a really high chance on, or when I really wanted to see both outcomes on a red check. The only required checks in the game give you hundreds of bonuses if you explore the area around them first.

When it comes to save scumming for a more perfect route, I always like to let my first run in a game play out however it does, because that's my one chance to experience the game at face value, so suffering only makes it better. Then I make my second run a perfectionist run for the catharsis.