Technology
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There are 86 billion neurons in the human brain and 16 billions in the cerebral cortex. More importantly, there are 100-1000 trillion synapses, and we know that parts the dendritic tree do independent computations as well. The computations are not synchronized with a global clock, but 1 ms events correspond to a kHz refresh rate and we know spikes can do temporal coding. Meanwhile, the best we can do is Cerebras CS-3 and with WSI at 5 nm there isn't much more where that came from.
Try doing the math on how many CS-3 you'd need to represent and refresh the above.