I'm about to finish up a Pathfinder 2e conversation of the 5e module Curse of Stradh. My players all decided to make my life hard and play as skeletons. It's made for a very unique campaign as I've had to think outside the box for how all the , normally, friendly NPCs would react to undead "heros". There's a lot of undead in the campaign and my players took a feat that essentially lets them try diplomatic solutions with undead before they become hostile. It's made encounters that should be combat into diplomatic missions and what should be safe places with friendly NPCs into high stakes (pun intended) stealth missions with potential for combat. The damsel in distress was horrified when she discovered her heros were undead and now has trust issues. Items the module sprinkles around are all for living heros to fend off the undead, so there's so much less help for my players and some of the help is more of a hindrance or outright deadly for them now. It's completely changed the dynamic of the module in such an interesting way and both my players and I have loved it.