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Bugchasing: intentionally infecting yourself with HIV
(en.wikipedia.org)
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Yes. There's different medications available for prep each with its own trade-offs. The vast majority of them can potentially antagonize the liver, so it's important to monitor liver function well on prep. As well as periodic HIV screenings, prep is for pre-exposure only. If somebody has HIV already, prep is not what they should be using, could be detrimental, hence the HIV screenings.
As of all medications, each individual must balance the pros and cons, and their net risks based on their activities.
Someone in a committed relationship probably does not need to consider prep, someone with multiple sexual partners who have in turn multiple sexual partners are great candidates for prep and the trade off it presents