I produced an album doing exactly this. the windows VST plugins with yabridge run like shit. not all of them worked. bitwig and reaper are fantastic though, and are great examples of what linux audio could be. unfortunately I am often using tools besides the daw and its built in features.

I should mention that yabridge folks are amazing. they are very responsive on IRC and they helped a lot. I think the main developer has pulled off something important here and I have a very high level of respect for what he's doing. i have to put my music before my computer though.