Pitch for an episode. Find a rogue starship lost decades ago and the crew is just hundreds of copies of the old transporter chief who found himself the only survivor in a past disaster. Desperate, he did the only thing he could think of to crew the ship and satisfy his loneliness. After so many years of churning out copies of himself from the decaying version in his buffer, he now believes himself to be the ideal humanoid being.

A transporter accident made a Vulcan scientist die screaming. A Vulcan. One can only imagine how excruciating that pain must be for a Vulcan to scream.

McCoy would never get in a car, or fly in an airplane, either.

We obviously haven't seen all of the transporter accidents, but given the implied frequency of use, the chances of bad outcomes are probably pretty low. Probably lower than being randomly killed in an away mission, since that happened to someone almost every episode.

Lt Barclay has entered the chat

I teleported home one night
With Ron and Sid and Meg
Ron stole Meggie's heart away,
And I got Sidney's leg.

... rest in peace, you hoopy frood

Eddington put them in the holosuite. If he hadn't they'd just be more names added to the forgotten list of transporter accidents. The only abnormality being that O'Brian wasn't working the transporter controls when this accident happened.

On the upside, it could also be used to finally murder Tuvix

And yet, they're juuust reliable enough that billions (possibly trillions) continue to use them on a regular basis. A roll of the dice for convenience and expediency.

Time to point out that a perfectly functioning transporter is probably a suicide machine.

I'd give anything to see a McSpock episode. Kirk would probably just phaser him/them on the spot.

I wonder if the transporter computer could make the same mistakes as AI image generation

The potential for the possibility that every time someone is taken apart into their constituent molecules, they simply stop living and upon reconstitution are replaced by an identical copy who thinks they are they while the original character is simply dead.

OK but the tuvix thing only happened because of that plant. So really just separate plants from people when transporting, problem solved.