Atelopus-zeteki

joined 10 months ago
[–] Atelopus-zeteki@fedia.io 20 points 1 week ago

He's not the first one to 'kill his liver' with paracetamol/ acetominophen (tylenol). First case I recall, the person was taking tylenol nightly with a glass of wine. Here's some links on the current understanding of Liver injury and paracetamol:

Apparently it's not always overdosing: Paracetamol-induced hepatotoxicity at recommended dosage (https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2003.01097.x)

Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update (https://pmc.ncbi.nlm.nih.gov/articles/PMC4913076/) "...in the United States, in particular, it accounts for more than 50% of overdose-related acute liver failure and approximately 20% of the liver transplant cases."

Risk Factors for Hepatotoxicity Due to Paracetamol Overdose in Adults (https://www.mdpi.com/1648-9144/57/8/752) "In the univariable analysis, significant hepatotoxicity risk factors were male gender, alcohol abuse, an ingested paracetamol dose, and a timespan from ingestion to hospital admission. The later one was the only significant risk factor in the multivariable model (adjusted odds ratio 1.08; 95% CI: 1.03–1.12)."

Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease (https://pubmed.ncbi.nlm.nih.gov/37436926/) "Where data were available, we estimate that paracetamol is involved in 6% of poisonings, 56% of severe acute liver injury and acute liver failure, and 7% of drug-induced liver injury."

Understanding paracetamol-induced liver failure (https://link.springer.com/article/10.1007/s00134-014-3293-9)

[–] Atelopus-zeteki@fedia.io 2 points 1 week ago

Correlation is not causation. Sometimes folks can't help but see what they want to see. I mean is it really "got some ganja", therefore "better go rent a hotel room." If so then wouldn't there be other indicators of increased tourism.

[–] Atelopus-zeteki@fedia.io 12 points 1 week ago (1 children)

Are you saying Texas Always Chickens Out?

[–] Atelopus-zeteki@fedia.io 8 points 1 week ago (6 children)

Can we dose them with Ecstasy while they are all gathered together? Or should we nuke them from space? I'm really torn on this one.

[–] Atelopus-zeteki@fedia.io 2 points 1 week ago

Snorfing amoebae up one's nose turns out to have consequences.

[–] Atelopus-zeteki@fedia.io 14 points 1 week ago

Traitor Felon in Chief

[–] Atelopus-zeteki@fedia.io 24 points 1 week ago

Sounds like is sure could be. Also sounds like the basis for a court case.

[–] Atelopus-zeteki@fedia.io 3 points 1 week ago

LoL, NOPE! I din' should on nobody!

[–] Atelopus-zeteki@fedia.io 5 points 1 week ago (3 children)

Sort of like the Weather Rock idea.

[–] Atelopus-zeteki@fedia.io 3 points 1 week ago (2 children)

Also 'tomo' is a prefix meaning cut, e.g. Computed Tomography.

[–] Atelopus-zeteki@fedia.io 3 points 1 week ago

LoL, thank you for that!

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