sovietknuckles

joined 4 years ago
[–] sovietknuckles@hexbear.net 6 points 2 weeks ago* (last edited 1 week ago)

the asahi mess is limited to M1/2 models

As of the Asahi Linux blog post from 2 days ago, they're working on SPMI controller support, which is part of M3 support.

I wouldn't really call Asahi a mess, they upstream their patches to the Linux kernel and are a part of the Fedora project. Also, Linus uses Asahi Linux for his travel laptop, a MacBook Air.

which are like 5 years old at this point.

M2 models were released in June 2022, they aren't 3 years old yet.

[–] sovietknuckles@hexbear.net 38 points 2 weeks ago* (last edited 1 week ago) (1 children)

One user said

I’ve always said that the best route to take when you’ve been accused of supporting genocide and apartheid is to double down

The reason they gave for removing that comment and banning him was

baseless accusations of zionism

even though his comment didn't mention Zionism

[–] sovietknuckles@hexbear.net 4 points 2 weeks ago (2 children)

I struggled with this, but I overcame it accepting that I am late to everything

[–] sovietknuckles@hexbear.net 7 points 2 weeks ago (1 children)

From the thumbnail I thought this was about Ukraine

[–] sovietknuckles@hexbear.net 8 points 2 weeks ago* (last edited 2 weeks ago) (1 children)

I wonder what your boss thinks about

  • Theo Von's episode with Hasan a couple months ago
  • Theo Von's episode with Candace Owens the week before that
[–] sovietknuckles@hexbear.net 23 points 2 weeks ago* (last edited 2 weeks ago) (4 children)

If Democrats hadn't cheated in 2016, Bernie would have won in 2016 and 2020.

If Democrats hadn't cheated in 2020, Bernie would have won in 2020 and 2024.

Simple as

[–] sovietknuckles@hexbear.net 57 points 2 weeks ago* (last edited 2 weeks ago) (16 children)

reddit-logo is being normal

Title: Hasan claims he had troubles entering the US because people make videos showing his content

He says he chooses his words very carefully, so why would he care if his content is widely shared and repeated? Either he stands by what he says, or he doesn't.

Instead of blaming YouTubers for "working with" the Trump admin, take a more critical look at your own rhetoric.

The slop tubbers that are using your own words?

This also brings up a good question: you are rich enough to peace the fuck out of America (a place that you hate). Why stay? Move to Canada or somewhere else in the world. I don’t understand why you would stay in America.

You can still shit in America from England or somewhere.

Last thing, Hey Hasan I’m sure you are reading this. Hopefully you don’t put the mask back up again. Say it with your chest, at least people will respect you for that

Insert sowing/reaping meme here

Send em to CECOT.

Good if true, but its not. Hes just a baby.

As a Turkish American naturalized citizen who abhors MAGA, I would have no qualms if Hasan had a one way trip to El Salvador. He is the walking textbook definition of a fifth columnist. He is more fanatical about Hamas than the average Palestinian.

[–] sovietknuckles@hexbear.net 1 points 2 weeks ago

floss.social is a Mastodon instance for people who care about, support, and build Free, Libre, and Open Source Software (FLOSS). It has 787 monthly users.

[–] sovietknuckles@hexbear.net 2 points 3 weeks ago

That's true. I cross-posted from r/Hasan_Piker, but I should have been more critical of the source. I'll delete it now

[–] sovietknuckles@hexbear.net 10 points 3 weeks ago* (last edited 3 weeks ago)

Probably just renaming Gaza to Palestine because "without the presence of Hamas" is unenforceable if Palestine has autonomy. They didn't say anything about independence or autonomy, so his goal might be to turn Gaza into another 2-state solution like the West Bank.

 

https://web.archive.org/web/20250125031358/https://www.newsweek.com/donald-trump-impeachment-free-speech-people-2020221

The article

Why It Matters

The renewed push for Donald Trump's impeachment underscores the deep political divisions in the country and the ongoing fallout from his campaign.

What To Know

An effort to impeach Trump has been launched by the non-partisan organization Free Speech For People.

According to the group, which is the parent organization of the "Impeach Trump. Again" campaign, Trump's return to the White House "poses an unprecedented threat to our democracy."

The group claims that Trump is disqualified from the presidency over his role in the January 6 Capitol riots under the 14th Amendment, which states that anyone, including the president, who takes an oath of office to uphold the Constitution and then engages in insurrection is disqualified from future public office.

Trump has pleaded not guilty to all charges against him related to the events of January 6. A Supreme Court ruling also found that former presidents have broad immunity from criminal prosecution for actions that are considered official duties, putting a significant roadblock in the way of the case against him, which has now been dropped.

However, a report by former special counsel Jack Smith recently found that there was enough evidence to prosecute Trump had he not been reelected.

Meanwhile, Free Speech For People also claims that Trump violated the emoluments clauses of the Constitution, which limits what gifts and titles federal officials can receive.

"Trump has refused to sell his ownership stake in companies through which he is assured to receive substantial payments from foreign governments in violation of the Foreign Emoluments Clause," Free Speech For People claims.

"At least five foreign governments pay a combined $2 million per month in fees for their units in Trump World Tower; and because all five of these foreign governments are currently paying Trump these monthly fees, Trump is in violation of the Foreign Emoluments Clause from the moment he took the oath of office."

The Trump Organization previously said that Trump would hand over daily management of his multibillion-dollar real estate, hotel, golf, media and licensing portfolio to his children when he enters the White House. The same arrangement was made during Trump's first term.

Additional allegations were made by the Impeach Trump campaign. Again these include claims of campaign finance violations, including offering tax and regulatory benefits to oil and gas executives in exchange for $1 billion in contributions, concealing legal service payments, coordinating with super PACs funded by billionaires later appointed to key positions, and accepting unlawful contributions from Elon Musk through X and a lottery scheme.

The group has also highlighted Trump's use of racist and xenophobic rhetoric, such as referring to immigrants as "bloodthirsty criminals" in Colorado, spreading false claims about Haitian immigrants in Ohio that led to threats of violence and blaming immigrants for "horrendous crimes" linked to "their genes."

Additionally, they allege that Trump threatened violence against political opponents, journalists, protesters and a U.S. military commander, and that he spread dangerous disinformation about hurricane disaster responses.

Trump's Previous Impeachments

During his first stint in the White House, Trump was twice impeached by the Democrat-controlled House, the first time in 2019 over his alleged attempt to pressure Ukraine to investigate then-candidate Joe Biden and the second in January 2021 over his role in the January 6 attack on the U.S. Capitol.

He was acquitted by the Senate in both cases.

Could Trump Be Impeached Again?

Impeaching and removing a president from office has never been accomplished and remains unlikely unless one party controls both chambers of Congress by wide margins.

Currently, the Republicans control both the House and the Senate, making a third impeachment very unlikely.

What People Are Saying

John Bonifaz, President of Free Speech For People, said: "Trump's return to the White House poses an unprecedented threat to our democracy. During his campaign and in the months before his inauguration, Donald Trump engaged in unlawful, unconstitutional conduct and threatened more.

"He has once more positioned himself to abuse the office for personal profit and power in violation of clear constitutional commands and at the expense of our democratic institutions, constitutional precedent and the safety of our country's most vulnerable."

What Happens Next

It is highly unlikely that Trump will see another impeachment while Republicans have control of both the House and the Senate.

But former Trump adviser Steve Bannon warned in November during an episode of his War Room podcast that House Minority Leader Hakeem Jeffries, a New York Democrat, would lead the charge to another Trump impeachment if House control flips during the midterms in 2026.

"Hakeem Jeffries could be, will be, the speaker of the House in two years," Bannon said. "And the first thing he will do in the early days of 2027 is move to impeach Donald Trump. Trust me. They're gonna put $10 billion in back of him. They have nobody else."

He continued: "… Hakeem Jeffries is just sitting there, right? He's ready to go. The [billionaire Democratic donor] Reid Hoffmans of the world are gonna put $10 billion in back of him to win a couple of seats, a handful of seats, in places that are kind of Democratic anyway."

48
submitted 5 months ago* (last edited 5 months ago) by sovietknuckles@hexbear.net to c/hexbear@hexbear.net
 

I am not DOSing Hexbear, higher traffic from VPN IP addresses is expected because there's fewer IP addresses per user.

Rate limiting by IP address is an anti-privacy op

Edit: Maybe the rate limit can be increased for login requests?

26
:moral-victory: (hexbear.net)
submitted 5 months ago* (last edited 5 months ago) by sovietknuckles@hexbear.net to c/emoji@hexbear.net
 

It's #2 on r/all right now

There's still some popular ghouls

I have United through work and was considering investing because they deny everything the first time. They also jack up the copay for services that are covered, like physical therapy, with no notice. Definitely one of the most greedy insurers.

If a company can drive its customer base into so much debt they resort to assassinating the CEO, that's an indication of a very strong business model.

https://old.reddit.com/r/wallstreetbets/comments/1h6leat/ceo_gets_gunned_down_in_the_street_outside_an/

.Originally posted !gossip@hexbear.net, but was removed for being posted in the wrong community

 

Summary: I've been taking metformin for months as protection against long COVID. I still mask everywhere, and I still take other COVID precautions, like nasal sprays, neosporin, air filters, Stoggles glasses, and getting a COVID vaccine. I am at high risk for severe COVID and long COVID, and I still plan to take paxlovid and use CPC mouthwash and nasal sprays if I get a COVID infection.

Why immediate-release metformin when paxlovid exists?

Paxlovid is harder to get outside of the US, and if you don't have health insurance or your health insurance doesn't cover it, it costs a lot.

Metformin is the second most commonly prescribed drug in the world (typically prescribed for type 2 diabetes or weight loss). So, lots of doctors prescribe it, and it is one of the least expensive medications out there.

Also, a paper published to the New England Journal of Medicine earlier this year found that Paxlovid is less effective than previously thought:

The time to sustained alleviation of all signs and symptoms of Covid-19 did not differ significantly between participants who received nirmatrelvir–ritonavir and those who received placebo.

so using both paxlovid and immediate-release metformin at the same time might not be redundant (and they don't interact with each other).

How effective is immediate-release metformin for COVID treatment?

There have been previous papers analyzing metformin's effectiveness for treating COVID, but the most notable study done on metformin in COVID patients (COVID-OUT) had a paper published this last May to Oxford University Press journal Clinical Infectious Diseases: Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19:

In the COVID-OUT randomized trial for outpatient coronavirus disease 2019 (COVID-19), metformin reduced the odds of hospitalizations/death through 28 days by 58%, of emergency department visits/hospitalizations/death through 14 days by 42%, and of long COVID through 10 months by 42%.

The mean SARS-CoV-2 viral load was reduced 3.6-fold with metformin relative to placebo [...]. Those who received metformin were less likely to have a detectable viral load than placebo at day or day 10 [...].

Viral rebound, defined as a higher viral load at day 10 than day 5, was less frequent with metformin (3.28%) than placebo (5.95%) [...].

Why immediate-release metformin? What about extended-release metformin?

Extended-release metformin might be ineffective for treating COVID, but we don't know for sure yet.

Conversely, an abandoned randomized trial testing extended-release metformin 1500 mg/d without a dose titration did not report improved SARS-CoV-2 viral clearance at day 7 [20].

They have a whole paragraph explaining the flaws of the failed extended-release metformin COVID study (the "Together Trial"), like randomizing people who were already taking metformin into the placebo or more metformin groups. The failed extended-release metformin/COVID study also had participants of that study start at the target dose of 1500mg/day extended-release metformin from the beginning, rather than starting at a lower dose and gradually increasing (an absolute must for metformin), which surely increased side effects.

Besides the flaws in the failed extended-release metformin/COVID study, immediate-release metformin might be more effective for your immune system:

Immediate-release metformin has higher systemic exposure than extended-release metformin, which may improve antiviral actions, but this is not known [24, 25].

So, immediate-release metformin is the thing that we know works for treating COVID, and there is no clinical evidence yet that extended-release metformin does, though that might change in the future.

There's also recent discussion in r/ZeroCovidCommunity on immediate-release metformin vs. extended-release metformin.

How to get immediate-release metformin and use it for COVID treatment?

How I did it: This last summer, I sent the immediate-release metformin/COVID paper to my endocrinologist and asked them to prescribe me metformin, and I have been taking it ever since. I take extended-release metformin because it has milder GI system effects, but if I get COVID, I will switch to immediate-release metformin for awhile.

Getting a metformin prescription might take time, so if you already have COVID, it's probably too late to consider metformin. There's lots of other reasons to take metformin, like slowing aging/living longer, lowering cancer risk, and lowering dementia and stroke risk, so in theory there's nothing wrong with taking metformin regularly without having type 2 diabetes, rather than starting once you get COVID. Speaking only for myself, I continually take extended-release metformin for its preventative effects, and I do not have type 2 diabetes.

Diabetes is one of the most common diseases for endocrinologists to treat, and metformin is the most common type 2 diabetes medication, so an endocrinologist/endocrine doctor is probably your best shot, if you already have one. Otherwise, you could ask your primary care doctor.

It goes without saying, but you don't have to mention COVID treatment as the reason to be prescribed immediate-release metformin, you could mention slowing aging, lowering cancer risk, or lowering dementia risk as a reason.

There are websites like AgelessRx that are willing to prescribe metformin for $75 to slow aging (that's the option of choice by r/ZeroCovidCommunity if you don't have a doctor who is willing to prescribe). Maybe they would be willing to prescribe immediate-release metformin, specifically.

Starting metformin once you get a COVID infection should be effective if you start within the first week of symptom onset (that's the metric that the study used), as long you were prescribed it in advance so that it's available to you right away.

How much immediate-release metformin to take?

That's a conversation for you to have with your doctor. The important thing, though, is not to take too much metformin. I briefly made that mistake, and it made me develop a taste aversion to one of my previously-favorite foods, and temporarily reduced my appetite so that I stopped eating enough food until the dosage was lowered again. Taking too much metformin per day also shortens your lifespan instead of increasing it, so don't take too much per day.

Who should not take metformin?

Something to know about metformin is that, if you are vitamin B12-deficient or your kidneys don't work well, metformin can give you lactic acidosis.

So if you have any kidney damage or any kidney disease, taking metformin is probably a bad idea.

Avoiding B vitamin deficiency

In my case, I take a B complex supplement that includes thiamine, B6, folate, and B12. My understanding is that if you supplement B vitamins, you don't need to worry about anemia, lactic acidosis, or other things that metformin + B vitamin deficiencies can cause unless your metformin dosage is too high.

103
submitted 7 months ago* (last edited 7 months ago) by sovietknuckles@hexbear.net to c/dredge_tank@hexbear.net
57
submitted 8 months ago* (last edited 8 months ago) by sovietknuckles@hexbear.net to c/covid@hexbear.net
 

This mucosal/nasal vaccine is called MPV/S-2P and it is developed by the NIH's National Institute of Allergy and Infectious Diseases (NIAID). From a 2023 study:

A single dose of MPV/S-2P was highly immunogenic, and a second dose increased the magnitude and breadth of the mucosal and systemic anti-S antibody responses and increased levels of dimeric anti-S IgA in the airways.

Obviously don't dox yourself on Hexbear, but the phase 1 trial sites are:

Decatur, GeorgiaThe Hope Clinic of Emory University
Mineola, New York, United StatesNYU Grossman Long Island School of Medicine - Vaccine Center
Houston, Texas, United StatesBaylor College of Medicine

so if you live near one of those, maybe you can participate.

They want to enroll 60 people, no clue how close they are to that goal

To try to enroll, contact them by phone or email.

 

The spray is called "Pathogen Capture and Neutralizing Spray" (PCANS) for now

This data suggest PCANS as a promising daily-use prophylactic against respiratory infections.

The study is paywalled, and the abstract doesn't list its ingredients beyond

The formulation consists of excipients identified from the FDA's Inactive Ingredient Database and Generally Recognized as Safe list to maximize efficacy for each step in the multi-modal approach.

Based on that description, its ingredients might not be very different from Covixyl, though it claims to be much more effective.

Edit: Apparently its already for sale, I included some details in a comment

view more: ‹ prev next ›