this post was submitted on 22 Jan 2026
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It is now 2:00 PM and, for the past week, I've been neither taking Vyvanse nor Abilify. I haven't taken Vyvanse for two weeks, in fact.

I felt good this morning, despite it all, and have been wondering if Vyvanse and Abilify has been negatively affecting me all this time and I just didn't know it.

Apparently, and correct me if I'm wrong here, you're NOT supposed to take both Vyvanse and Abilify together; they do NOT go together.

Can anyone provide me more information about this?

I am researching online about this combination, but I have cyber-chondria and so have trouble researching this stuff up on my own (it's hard to do the research when you have so much fear and what-not).

How does Vyvanse affect you mood-wise?

And how about Abilify?

How about both together?

I am Autistic with ADHD, probably OCD, and C-PTSD. I am transfem as well, but haven't done HRT. I also have SAD (Seasonal Affective Disorder). I'm 30 years old.

My psychiatrist is a "pill-pusher" and just gives me whatever medicine I ask for or just what's popular; I'm in Virginia and we're known for our bad and corrupt psychiatry and mental health institutions here.

People on Reddit keep telling me to "trust your pyschiatrist" or "talk to your psychiatrist" but my psychiatrist absolutely sucks.

I'm trying to ask for a second opinion from other institutions and psychiatrists.

I'm going through Abilify on Wikipedia and the results that it does on human beings seems abysmal, no offense to anyone here who might take it.

I just heard from a friend that Abilify made her feel absolutely awful during the time that she took it and even rageful.

It's used most often on Autistic people and I've been taking it for about 10 or so years; I feel great without it. I realize that the sudden happiness comes from NOT having it at all.

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[–] o_d@lemmygrad.ml 6 points 4 days ago* (last edited 4 days ago)

I was prescribed abilify for depression. I have medication resistant major depressive disorder and no antidepressants I've tried have been helpful. I was on it for 1 month and gained 50lbs. I was also a bit of a zombie while I was on it. It helped my anxiety, but I have to imagine this is a side-effect of the zombification and not the medication directly resolving it.

I also have CPTSD, and I'm beginning to believe that antidepressants aren't really made for us, but for the larger portion of society that's just depressed because of their subjugation to the capitalist system. The only thing that's been helpful for me is therapy, but that's a long term solution for sure. I'm doing a clinical trial where I'll be receiving psilocybin assisted therapy. I've also had good results with self medicating psychedelics, so I'm hopeful that this will be at least somewhat effective.