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LD50 is like 1-2mg.
I saw a local advocate or social worker that went to the streets in Portland to get a first hand acct of when fent first hit the streets. Guy said that there was talk that a dealer had had 4 ODs on his batch and everyone went looking for it cause, you know, good stuff. That first wave killed about 60% of users that had less than a year of heavy use(tolerance, he called them new friends), but those that survived had built up their tolerance. So after it was gone everyone went back to the old regular heroin and it didnt quite hit. Users were pissed cause they were buying twice as much for nothing.
Second wave had less ODs because survivors had built up a tolerance, but there was still a lot. He said it was either less savy addicts that didnt take a test batch first before going up or impatient addicts that hadn't had a good fix and had just been keeping withdrawals away. He saw a guy he shot up with that was 36 hrs into withdrawals. Take a higher dose than normal, so he could actually get high. That he smiled, laid out and started snoring about 2 minutes later. Probably died soon after cause he stopped breathing.
He said all serious addicts can't go back to regular heroin and that some ppl,like him, take 2 light doses for withdrawals and to lower tolerance and take a normal dose to get high and the high isn't the same. That its short and causes a lot of nausea. He wished he could somehow lower his tolerance and go back to heroin, but dealers dont sell non fent heroin cause no one wants it.