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A Popular Sweetener Was Linked to Increased Anxiety in Generations of Mice
(www.sciencealert.com)
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this post was submitted on 25 Dec 2023
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It said it was like 15% of human recommended intake.
Sorry legit haven't read the article but sounds like you have, so I'll ask for clarity
Would that be the equivalent of a 15% daily recommended dose, as adjusted by weight for a rat, or is it literally 15% of the daily allowance of a human, pumped into the rat? Because the latter is definitely more of what vibe I get from the previous poster.
Cool, so it's 15% of the RDA for humans, divided by whatever the avg weight difference between a rat and a human is, right? Or similar? That's the best interpretation of that quote, though it is still a bit ambiguous lol
I read it as the rat equivalent of 15% for humans.
Yeah, that's what I get now. I would like if they had a more specific rundown of how that number was calculated, and how much water it was in / the rats consumed. May be in the article or study, still haven't actually read it and don't have the time ATM.
That quote makes it sound like it's not adjusted by weight. But it also doesn't mention the aspartame to water ratio, or how much of the water that the rats drank.
Here's the relevant sentence in the study:
It's a lot to unpack, but my interpretation is that it's been adjusted for a rat
To translate that into something sensible, the RDA in the US is 50 mg/kg = 110.25 mg/lb. 15% of that is 16.5 mg/lb. So 1653 mg per 100 lbs of bodyweight.
A can of diet coke is about 200 mg of aspartame. So that's a bit over 8 cans of coke per 100 lbs of body weight. Or 1.5 2-liter bottles per 100 lbs.
That's... kinda a lot.