I recommend CrossCode. It's a puzzle-heavy top-down action-RPG. Think 2D Zelda games, but faster paced and sci-fi themed. You play as Lea, an amnesiac who's trying to recover her memories by playing a fictional MMO called CrossWorlds. I love basically everything about it: the art, the music, the characters, the story, the puzzles, the level design; it's just great.

Castlevania: order of ecclesia

Cross code

Oceans heart

Alice games

Stardew valley

There's this weird game from a while back that didn't get much hype.

You'll find it either as "The Experiment" or "Experience112". Got some interesting mechanics, which later influenced another niche game I just realized has a female protagonist: Republique.

Technically, you don't play as a female protagonist. But you're essentially not the main character and you have no discernible physical features anyway, so you could just apply whatever gender you want to whoever you think "your character" is.

It's kind of like... "Female protagonist by proxy". I feel like that's a decent description. The point is that the main character is a (generally) well-written lady protag.

"good" is subjective, but I can recommend the Tomb Raider reboots.

Whoa whoa whats wrong with Senua?

I really liked the Edna & Harvey games

It Takes Two has a great protagonist

Final Fantasy X-2 comes to mind. I didn't finish it, but it's well-reviewed so...

Most games I can think of have been mentioned, but I found Signalis to be an interesting experience assuming you can get past the annoying inventory management

Dreamfall: The Longest Journey. After playing it for a while I couldn't stop until I reached the end. It looks aged now but controls are generally nice and the story is amazing.

Eternal Darkness: Sanity's Requiem. You play as many characters, but the primary main character is Alexis Roivas.

There's Alien: Isolation if you're looking for a horror game. Every so often I'll go and give it another playthrough. That game was phenomenal, especially if you're a fan of the Alien movies

Forspoken isn't bad.... As long as it's played completely dubbed in Japanese with subs on. Obviously last of us 2 was really great, horizon is also very well acted, and very well done. I think it also is inclusive in a way that matters where some games just replace the protag with a woman, these games build it into narrative as well. In the same vein, I really liked life is strange (even colors to be honest)

This is a very obscure one, but there is a mod for Freespace 2 called Blue Planet: War in Heaven which has an amazingly well written story and female lead.

A lot of good suggestions here. Remember Me and Mirror's Edge are also good, perhaps not as great some of the truly outstanding ones already posted though. But if you're looking for something with a cyberpunk edge, both will fit the bill nicely.

Kena: Bridge of Spirits is good. I still gotta finish it, but I've enjoyed it so far.

How about Final Fantasy XIII? The first game has a full sized party, but Lightning is clearly the main character and the focus. Second game costars Lightning's younger sister and a new male character. Third game is just Lighting.

@Mandy

Bayonetta 1 and 2.
Perfect Dark
Half-Life: Alyx

Just an FYI on the NOLF bit...

http://nolfrevival.tk/

Celeste!

By NOLF you mean No One Lives Forever? If so a quick search gave me this "revival" site, seeing the Windows targets i bet that runs on Wine