this post was submitted on 20 Jun 2026
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HR is hazard ratio, a term often used in observational epidemiology to express event hazard of the variable. The core problems is these studies are not tightly controlled, have innumerable confounders, and 1.12 means a 12% increased relative risk (not absolute risk)... which is so low it might as well be noise. This is a useful tool in the scientific process to generate hypotheses to plan further interventional experiments with, but it cannot establish cause and effect. However, lots of people REALLY REALLY REALLY want to use such data to make claims of cause and effect.
Most nutritional papers are exactly this. Dr Bradford himself, the main who came up with the smoking->cancer link and wrote the definitive criteria for observational data, even indicated a hazard ratio less then 2 (so 200%) isn't meaningful.
MD Ede explains this so much better then I can https://www.diagnosisdiet.com/full-article/epidemiological-studies
Update - Here is probably one of the best published illustrations of this weakness - https://doi.org/10.3945/ajcn.112.047142 - Is everything we eat associated with cancer? A systematic cookbook review
Thanks! I actually used to teach stats - at least for awhile ๐. I just came across the meme and that didn't click for an association.
That is a great explanation by the way. More coherent than I think I could manage.
Cigarette smoking has a hazard ratio of 7 (700%) for lung cancer, for comparison.