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Oxygen
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this post was submitted on 17 Sep 2024
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Aliens would need an oxidizer to metabolize as well, even if that oxidizer isn't oxygen. If they want to actually efficiently get energy out of things, it'll need to be a strong one. Even fermentation is a oxidation-reduction reaction that just doesn't use oxygen.
If we ever found a species that was made of alcohol we would absolutely dominate, err domestic them as quickly as possible.