this post was submitted on 25 May 2026
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[–] atzanteol@sh.itjust.works 49 points 2 days ago (3 children)

“Naturally occurring ascorbic acid and added ascorbic acid — which may be chemically manufactured — may have different impacts on health,”

This article reeks of MAHA "naturalistic" bullshit.

[–] AnimalsDream@slrpnk.net 7 points 1 day ago

Not necessarily. It is known that some vitamins can have differing effects depending on whether they're in whole food form, or in a supplement.

Haven't read the article yet, but my suspicion would be more correlation than causation. Those industrially manufactured ascorbic acids virtually always end up in highly processed foods, and that's what is more likely the main harm.

[–] Imgonnatrythis@sh.itjust.works 27 points 2 days ago (2 children)

Go right to the actual scientific article. It doesn't seem to include this sort of nonsense. It's a seemingly well put together but herculean effort to try to study this. They do a nice job controlling for known covariables, but it's very possible they are missing a linked factor. Using this as a basis for a randomized study with these chemicals would be truly interesting.

[–] Photonic@lemmy.world 5 points 2 days ago* (last edited 2 days ago) (1 children)

I beg to differ. From the manuscript:

Despite food additive ascorbic acid and alpha-tocopherol having identical structures to their naturally occurring forms,[3]() their effects can differ based on factors such as food matrix (composition, structure, etc.), dosage, and interactions with other food compounds affecting bioavailability.[52]

[–] Imgonnatrythis@sh.itjust.works 3 points 2 days ago (1 children)

This is probably where the science writer derived this from. This is so much clearer though that it's not the origin of the compound that matters so much as the environment it is in.

[–] Photonic@lemmy.world 1 points 1 day ago* (last edited 1 day ago)

Yes but they still say that:

food additive ascorbic acid and alpha-tocoperol

Vs

their naturally occurring forms

And that

their effects can differ

So it’s not like the part the writer talked about wasn’t almost literally mentioned in the paper.

They are also just quoting the senior author, since the part of the article the guy you replied to omitted was:

“said Touvier, who is also director of research at France’s National Institute of Health and Medical Research in Paris.”

Scientific papers will always be dumbed down a bit and information will be omitted when writing an article for the general public.

The guy you replied to simply doesn’t know what he is talking about and thinks he knows better than the senior author.

[–] atzanteol@sh.itjust.works 4 points 2 days ago (1 children)

Aye - the article is hot garbage. Science reporting is a complete mess.

[–] A_Random_Idiot@lemmy.world 2 points 1 day ago* (last edited 1 day ago)

Yep.

Entirely because people try to sensationalize it to make it interesting and exciting, and usually jump on it before theres even been other studies to confirm the results or not.

Which results in a lot of fatigue.. Like how people are, to this day, still confused about if eggs or good or bad because the flood of studies in the 90s, each contradicting eachother about eggs being good, eggs being bad, this part of the egg being good, that part being bad, etc etc.

[–] minorkeys@sh.itjust.works 1 points 1 day ago

Running interference for the corporate food industry, of course. Don't sue them, let them reduce their liability first.

[–] blimthepixie@lemmy.dbzer0.com 74 points 2 days ago (3 children)
[–] AyuTsukasa@lemmy.zip 32 points 2 days ago (5 children)

Vitamin C is a preservative?

[–] atzanteol@sh.itjust.works 33 points 2 days ago (1 children)

Yep. As are salt, vinegar, alcohol and other common foods.

You ever squirt lemon juice on an avocado to keep it from browning for a bit?

People love to use the phrase "preservative" to mean something bad. But it's just anything that helps to keep food from spoiling.

[–] SaveTheTuaHawk@lemmy.ca 6 points 2 days ago (2 children)

You ever squirt lemon juice on an avocado to keep it from browning for a bit?

That's citric acid.

[–] atzanteol@sh.itjust.works 15 points 2 days ago

Yes - it's a preservative.

[–] PapaStevesy@lemmy.world 7 points 2 days ago

And ascorbic acid.

[–] Jajcus@sh.itjust.works 31 points 2 days ago (1 children)

It is an antioxidant. And oxidation is one of the way food goes stale.

[–] CmdrShepard49@sh.itjust.works 2 points 2 days ago

That explains why food is so stale in the rust belt.

[–] titter@lemmy.world 11 points 2 days ago (1 children)

It is acidic, which is a common preservation method as it reduces the amount of bacteria that can find the citrified food as hospitable.

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[–] msage@programming.dev 10 points 2 days ago (1 children)

Ohhh yes.

It enables everyone to put 'now with vitamins!' on labels.

[–] comrade_twisty@feddit.org 4 points 2 days ago

Doea it have electrolytes though?

[–] slaacaa@lemmy.world 2 points 2 days ago

I haven’t clicked the article, but it’s probably ascorbic acid. Very common preserver, as it acidifies the food and kills bacteria

[–] lauha@lemmy.world 5 points 2 days ago (1 children)

Specifically synthetic vitamin C, not naturally occuring.

[–] Greyghoster@aussie.zone 2 points 2 days ago (1 children)

The interesting bit the unsupported claim there is a difference between manufactured and naturally occurring vitamin C. This goes on to say fruit is good but everything else is not. A long bow to draw.

[–] lauha@lemmy.world 4 points 2 days ago (1 children)

Not sure if you are familiar with the sibject but chirality is a thing and nature usually prefers one chirality of a molecule while synthetic processes often produce both chirality.

[–] Greyghoster@aussie.zone 1 points 2 days ago

Thanks, I’ve heard about it but didn't know enough consider it.

[–] Photonic@lemmy.world 6 points 2 days ago (2 children)

Well yes, but the manufactered kind. This doesn’t mean naturally occurring vitamin C in fruits has the same effects. Vitamin C is an important nutrient and antioxidant when consumed in its natural form.

[–] Shayeta@feddit.org 30 points 2 days ago (3 children)

Ahh yes, natural ascorbic acid. Not to be confused with artifical ascorbic acid with the same exact molecular structure.

[–] SaveTheTuaHawk@lemmy.ca 6 points 2 days ago

that's not the point. Food origin ascorbate is delivered at a longer slower dose than popping a pill. Dosage matters.

[–] liuther9@lemmy.world 3 points 2 days ago

Ahhh yes, enantiomers

[–] Photonic@lemmy.world 3 points 2 days ago (2 children)

While antioxidants such as citric and ascorbic acid are found naturally in foods such as fruits, they are “not exactly natural” when used as preservatives, senior author Mathilde Touvier said in an email. Touvier is the principal investigator of the NutriNet-Santé study used to conduct the research.

Yeah I’m gonna go with the senior author here. But hang in there sport!

[–] BrianTheeBiscuiteer@lemmy.world 5 points 2 days ago (1 children)

Cooking isn't "natural" either by his definition. Next MAHA craze: No more cooking food? Just eat everything raw?

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[–] PapstJL4U@lemmy.world 2 points 2 days ago (1 children)

This does not describe them as acting different.

[–] Photonic@lemmy.world 13 points 2 days ago

Despite food additive ascorbic acid and alpha-tocopherol having identical structures to their naturally occurring forms,[3]() their effects can differ based on factors such as food matrix (composition, structure, etc.), dosage, and interactions with other food compounds affecting bioavailability.[52]()

[–] atzanteol@sh.itjust.works 11 points 2 days ago (7 children)

They're the same. If I gave you two molecules of C6H8O6 there is no way you could tell me how they were made and if one was "natural". Your body certainly wouldn't care either way.

[–] Photonic@lemmy.world 9 points 2 days ago* (last edited 2 days ago) (2 children)

I understand, but the article and paper clearly states that may not be the case.

Despite food additive ascorbic acid and alpha-tocopherol having identical structures to their naturally occurring forms,[3]() their effects can differ based on factors such as food matrix (composition, structure, etc.), dosage, and interactions with other food compounds affecting bioavailability.[52]()

[–] atzanteol@sh.itjust.works 4 points 2 days ago (1 children)

their effects can differ based on factors such as food matrix (composition, structure, etc.), dosage, and interactions with other food compounds affecting bioavailability.

That sentence literally says that there is no difference in the origin of the vitamin C and that the differences they're seeing are due to the food it is in (and potential interactions of Vitamin C with those foods). That has zero to do with whether the Vit. C is "natural" or not.

The shit article probably took her quotes out of context and/or misunderstood them.

[–] Photonic@lemmy.world 2 points 2 days ago (1 children)

It definitely says there’s a difference in origin. They say there’s no difference in chemical composition.

I also never said there was a chemical difference between the two, I just talked about the effects. Just like the manuscript.

[–] atzanteol@sh.itjust.works 3 points 2 days ago (4 children)

It definitely says there’s a difference in origin.

I worded that poorly - I meant "due to origin".

I also never said there was a chemical difference between the two, I just talked about the effects. Just like the manuscript.

Then riddle me this - how do two identical things have different effects?

The paper says it's not due to the origin of the chemical but due to interactions with other things in the food to which it was introduced.

It does not matter if the Vit. C was created in a lab, in a fruit, or divinely produced by God.

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[–] BenevolentOne@infosec.pub 4 points 2 days ago (1 children)

There is also a question of yield in various processes. One process could readily yield 99% ascorbic acid with 1% rapid and unmitigable death.

You have a lot of patience Photonic, to be willing to fight team science on scientifocity, especially since we all know it's really tiny elves which make some foods good to eat and others poisonous, and not, say, the effect of preservatives on gut microbiome.

[–] Photonic@lemmy.world 4 points 2 days ago (2 children)

I feel more like I’m fighting team “I read a thing once and am now going to bash someone just trying to make a small side note while not having read the article or paper” and not team “science”.

[–] atzanteol@sh.itjust.works 5 points 2 days ago (5 children)

"Team science" does not say "natural vitamin C is better than chemically created vitamin C". 🤣

That's the shit you get from pop science in a book sold on daytime television.

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[–] SaveTheTuaHawk@lemmy.ca 3 points 2 days ago

Team science of Lemmy is team, "I vaguely remember grade 11 chemistry".

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[–] Atelopus-zeteki@fedia.io 9 points 2 days ago

Preservative food additives, hypertension, and cardiovascular diseases: the NutriNet-Santé study https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehag308/8679203?login=false

Abstract Background and Aims Experimental studies suggest that some preservative food additives may exert adverse cardiovascular effects, yet human data are lacking. The associations between exposure to these compounds and incidence of hypertension and cardiovascular diseases (CVD) were investigated in the NutriNet-Santé cohort (France, 2009–2024). ..................................................................................................................................................................... Methods Dietary intakes were assessed using repeated 24-h dietary records (up to 96), including commercial brands. Exposure to food additives was evaluated through multiple composition databases and ad hoc laboratory assays in food matrices. Associations between cumulative time-dependent exposures to preservative food additives during follow-up and outcomes were characterized using multi-adjusted Cox models. ..................................................................................................................................................................... Results Overall, 112 395 participants were included (78.7% women, mean age 42.8 ± 14.7 years) with a median follow- up of 7.9 years. The sum of total preservatives encompassed 58 substances consumed by at least one participant. Total non-antioxidant preservatives were positively associated with higher incidences of hypertension [n = 5544; hazard ratio (HR) higher vs. lower consumers: 1.29, 95% confidence interval (CI) 1.20–1.39] and CVD (n = 2450; HR 1.16, 95% CI 1.04–1.29), while total antioxidant preservatives were associated with higher incidence of hypertension (HR 1.22, 95% CI 1.13–1.31). Out of the 17 individual preservative food additives consumed by at least 10% of the study population, eight were associated with higher incidence of hypertension and one with higher incidence of CVD, after multiple test correction. ..................................................................................................................................................................... Conclusions Multiple associations between exposure to preservative food additives widely used in industrial foods and higher incidence of hypertension or CVD were observed in this large prospective cohort. Experimental research is needed to gain insight into underlying mechanisms. If confirmed, these new data call for the re-evaluation of regulations governing the use of these additives to improve consumer protection. ..................................................................................................................................................................... Trial Registration ClinicalTrials.gov NCT03335644.

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