Uh... Why not?
this post was submitted on 08 Feb 2026
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Grapefruit disrupts metabolism by Cytochrome P450 enzymes in the liver. They are widely involved in drug metabolism. https://en.wikipedia.org/wiki/Cytochrome_P450
Doesn't it interact with... I can't remember if it was ecstasy or some normal medicine
Only thing that came to mind was diabetics can't usually have grapefruit. Is the joke that redbull enjoyers are diabetic? 🤔
Antidepressants, anxiolytics, stimulants, etc.
https://en.wikipedia.org/wiki/Grapefruit-drug_interactions#Incomplete_list_of_affected_drugs
And some birth control.
Some statins too
And my axe!
This guy grapefruits
He's gonna get the juice everywhere though!
A quality axe can cut grapefruit without mess, the big concern is keeping the axe clean. Grapefruit is hell on non-stainless metals.
I mean that lists off acetaminophen… and it says all citrus juices can do it, so don’t drink juice at all then?
Def drink grapefruit juice if you're taking e. The extra vitamins help a ton and it'll extend the high.
Also reduces the toxicity from the metabolites your body makes while processing it. Pretty convenient with all the other good ways they interact
Lots of answers but I think the explicit joke here is that grapefruit doesn't work with certain types of antidepressant medications, which redbull's clients are presumably on.
I thought it was the "girl" part since most women of reproductive age are on hormonal contraceptives.
2 minute sci-show answer why it isn't a good idea to mix certain medications & grapefruit.
Enzymes in grapeftuit can cause some medications in a safe dose to become too effective often in dangerous ways.
Are any of those drugs in Redbull, tho?
The implication here is that a consumer who is inclined to drink Redbull is likely the type of person who suffers from an affliction for which they are prescribed some sort of mood-regulating medication, many of which negatively synergize with grapefruit enzymes.
Isn't RedBull more associated with clubs and raves (and therefore liberal drug use)? At least that's how it used to be. RedBull vodka + a couple of sketchy pills and dance until the sun comes up.
I am not a huge fan of alcohol, but an ice cold jaeger bomb (jagermeister and redbull) is tasty af. Has to be ICE COLD tho. Room temp jager bombs suck.
did redbull really just release a new subliminal social media advert? girl your shitpost base can't HAVE adverts??
Advertisements in my lemmy shitpost community?
It’s more likely than you think.
i don't get why you're upset at people talking about products they enjoy
I don't get it
~~No grapefruit while taking ssri medication~~
edit: sorry, this is a bit misleading and an oversimplification
https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions
Wait...
I don't think that's true. If it were, they'd put it in the instructions that come with the SSRI medicines.
And it is not on the list of drugs on this web page. https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix
Yup, I made a bad generalization. My bad, and to be clear I'm not a doctor or anything.
Some SSRIs may have an interaction with grapefruit. But grapefruit interacts with different medications differently, and it's not based on the class of medication, it's med specific.
e.g. Sertraline (Zoloft) is an SSRI and is listed as having an interaction with grapefruit
https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions
Eta: thanks for calling that out, I've learned some interesting things, for example;
Ketamine: After drinking 200 mL of grapefruit juice daily for five days, the overall absorption of orally ingested ketamine was increased three-fold compared to the control group in a clinical trial. The peak blood ketamine concentration was increased over two-fold.
That is so weird. Here is the study: https://pubmed.ncbi.nlm.nih.gov/10890261/
It was only n=5 but my layperson understanding is that the results were significant.
Either I've never noticed a grapefruit warning (and at one time I read the documentation fully) or Sertraline doesn't come with one...
Some blood pressure and heart meds.
And contraceptives and some antibiotics and antivirals and....
I like grapefruit, but I gave it up ages ago.
I would be shocked if grapefruit flavored red bull contains any part of grapefruit the fruit.
I think the monster one has a little bit