141

my first estrogen shot!!! (hexbear.net)

submitted 5 months ago* (last edited 5 months ago) by ZoomeristLeninist@hexbear.net to c/traaaaaaannnnnnnnnns@hexbear.net

43 comments fedilink hide all child comments

nothings happened yet wtf! where’s my instantaneous magical girl transformation?

seriously tho, i expected some mental change based on how ppl describe the euphoria of being on E, but ig that takes time just like the physical changes.

i can wait tho, i was so indescribably happy last night after injecting. i was tearing up and cuddling with my gf and had amazing sleep. it feels like a new chapter of my life that im more optimistic and joyful for than ive ever been! been waiting almost two years for this moment 🥹

thank you hexbear! i dont know how much longer it would have taken for me to discover my transness if i wasn’t a part of the site with the best trans community on the internet!

and im moving to a medium sized city in a month so ill be in a good place to transition compared to the rural area where i live

i am DIY and made four vials a couple weeks ago. then yesterday i sterilized them at 130C for 30 minutes, pretty easy in oil if you have a digital probe thermometer (i think ppl call them candy thermometers).

my regimen is 11 mg estradiol enanthate stabbed into my butt every 14 days. im planning on getting a blood test in 3 months and adjusting. p sure ill have to up the dose bc im 6’ and 200 lbs. prob gonna try to add progesterone in 6 months to a year even tho the studies on that haven’t been too promising in it helping transfems. prog can actually be pretty cheap if you DIY and mix a powder with coconut/cocoa oil and take it rectally.

top 43 comments

sorted by: hot top controversial new old

[-] pooh@hexbear.net 18 points 5 months ago

CONGRATS!!!!!

i was so indescribably happy last night after injecting

I had a similar feeling after my first shot 3 weeks ago. Makes me super happy to hear about your own great experience. It's only going to get better from here. cat-trans

[-] ZoomeristLeninist@hexbear.net 10 points 5 months ago* (last edited 5 months ago)

when i saw u talk abt ur first shot it inspired me to finally get started after ive been doing nothing with my estrogen for months cat-trans

[-] pooh@hexbear.net 11 points 5 months ago

OMG YAY!!!! meow-hug

@Wake@hexbear.net was the one who inspired me and I can't wait until the next person is inspired by your post! bridget-pride

[-] ZoomeristLeninist@hexbear.net 10 points 5 months ago

may the trans train never end!

[-] wtypstanaccount04@hexbear.net 7 points 5 months ago

Damn it was just a little while ago that we were talking about you wanting to be a girl. Congrats, you're on your way!* trans-heart

*to society accepting you as a girl, we would accept you as a girl anyway meow-hug

[-] Dirt_Owl@hexbear.net 18 points 5 months ago

bridget-vibe noice!

[-] da_gay_pussy_eatah@hexbear.net 17 points 5 months ago

You say you didn't experience any euphoria, yet you cried with joy after injecting, curious 🤔.

But seriously though, yeah I didn't really feel a major shift but I definitely feel my emotions in such a satisfying way since starting hormones, and that came pretty quickly for me. It's kinda subtle though, and I haven't started on prog yet.

[-] ZoomeristLeninist@hexbear.net 13 points 5 months ago

lol i meant no euphoria today. just right after injecting

that sounds nice tho

[-] imikoy@hexbear.net 17 points 5 months ago* (last edited 5 months ago)

mental change expected

Do know that the intensity of the mental changes vary between different people. I know some people who did have big changes, and some who didn't. I don't have a concrete explanation for this.

injections into butt

I remember seeing recommendations of other places for injections, explained by the risk of damaging a nerve that runs in the glutes. But I also remember that there's a safe zone? Take care.

mixing prog with oil and getting it into the colon

hmmmmm...

Anyway, unlimited feminisation upon [she/her, they/them]'s of the Hexbear.

edit: added they/them

[-] ZoomeristLeninist@hexbear.net 11 points 5 months ago

if you inject in the upper, outer quadrant you avoid the sciatic nerve

[-] imikoy@hexbear.net 11 points 5 months ago* (last edited 5 months ago)

yeah, that place is supposed to be safe

(where is the emote for estradiol to pair with qin-shi-huangdi-fireball to send estradiol to the comrades)

[-] Shinhoshi@lemmygrad.ml 2 points 5 months ago

Anyway, unlimited feminisation upon [she/her]'s of the Hexbear.

Is there a gender therapist for a minute community here? Why am I sad that I wasn't included here...?!

I guess I have to change my pronouns now... how is Hexbear the only thing that ever moved me down the pipeline?

[-] imikoy@hexbear.net 1 points 5 months ago* (last edited 5 months ago)

Oh, sorry! I should have included they/them from the start, my bad

meow-hug

[-] Shinhoshi@lemmygrad.ml 2 points 5 months ago

I get why you didn't because not all they/them people would want that (especially AFAB enbies) but it just gave a push to experiment that I hadn't been willing to take before

[-] sharedburdens@hexbear.net 16 points 5 months ago

I'm a pill user myself but that rules party-blob

[-] FearsomeJoeandmac@hexbear.net 13 points 5 months ago* (last edited 5 months ago)

Really is probably the best community for trans people on the internet. Bonus points if you're a Marxist too. I'm not trans myself, but they are my friends and I love my friends.

[-] queermunist@lemmy.ml 13 points 5 months ago

I only started experiencing mental changes after starting progesterone 🤷‍♀️

[-] ZoomeristLeninist@hexbear.net 12 points 5 months ago

sweet!

[-] Findom_DeLuise@hexbear.net 7 points 5 months ago

Wild, mine started almost immediately on just E. Haven't worked prog into the regimen yet -- that's about another 5 months out, IIRC

[-] queermunist@lemmy.ml 4 points 5 months ago

I'm starting to suspect it's because I was on a very high dose of Venlafaxine, which flattened my emotions out a lot. The prog was what finally broke through the fog.

[-] Findom_DeLuise@hexbear.net 2 points 5 months ago

Yeah, that might do it. And full disclosure, I didn't really feel it when I first started off, since I was on fairly low-dose transdermal patches. After about a month of those damned things falling off, I switched to gel and hooooly shit that was intense. I spent those first few days pretty loopy, to say the least. Happy, but loopy -- apparently at one point on the first day, I almost blundered into a moving car while walking across a parking lot. I think TC69 described hir first experience on E as feeling a little like being high, and that definitely tracks for me -- as I am fond of saying, gender euphoria just feels like regular euphoria.

[-] HelltakerHomosexual@hexbear.net 12 points 5 months ago

fuckin congrats! Anticistamines are the best!

[-] pooh@hexbear.net 14 points 5 months ago

[-] Black_Mald_Futures@hexbear.net 12 points 5 months ago

Hey congratulations!

i expected some mental change based on how ppl describe the euphoria of being on E, but ig that takes time just like the physical changes.

i can wait tho, i was so indescribably happy last night after injecting.

I mean I'm not gonna tell you how to feel, but I think you're feelin' it little dawg

yesterday i sterilized them at 130C for 30 minutes, pretty easy in oil if you have a digital probe thermometer (i think ppl call them candy thermometers).

Not trans and not a chemist but I think if I had to do something like this with regularity I'd look into getting one of those like, chemistry hotplates, something that you can also set to a specific temperature, since that seems like it would be easier to use regularly than tweaking the temperature and checking with a thermometer.

I've thought about getting one but to make like marijuana tinctures instead, because it was a real pain in the ass using my candy thermometer (not digital) to get a water bath to the right temp to serve as a double boiler for the tincture

[-] ZoomeristLeninist@hexbear.net 9 points 5 months ago

it would be easier, but those four vials will last years so ill deal with the extra effort to avoid buying a hot plate

[-] Black_Mald_Futures@hexbear.net 8 points 5 months ago

Oh okay, I didn't know it'd last that long both in dosage or shelf life, that's cool

[-] Chronicon@hexbear.net 9 points 5 months ago* (last edited 5 months ago)

yeah its really neat if you're into that sort of thing (linky)

surprisingly easy to do yourself. If the linked post is to be believed 120+C is overkill, and just doing boiling water is much easier and self-limiting in temperature (I believe her but shrug-outta-hecks )

And the shelf life is aided by adding a bit of preservative like benzyl alcohol

[-] Black_Mald_Futures@hexbear.net 6 points 5 months ago* (last edited 5 months ago)

Either way imo absolutely do not sterilize an injection drug by just boiling water, and that includes like all the tools used to inject obviously

Im drunk r/n and haven't been in school for a decade but if i wanted to sterilize a needle i'd dip it in isopropyl alcohol and light it on fire. That was how we sterilized glass stirrers in my microbiology classes at least so i think it'd work okay for steel needles (uhhh idk what needles are made of maybe check that)

[-] Chronicon@hexbear.net 6 points 5 months ago* (last edited 5 months ago)

I mean pretty much everyone I've seen just uses one-time-use pre-sterilized needles to inject. Insulin needles are easy to get. I'm assuming that part is safe, if not we owe diabetics a huge apology.

Fire would not be a great idea, I think it would be likely to leave residue on the needle depending on the flame source, potentially mess up the heat treatment of the metal, etc. And thankfully not a concern with pre-sterilized needles.

[-] Black_Mald_Futures@hexbear.net 5 points 5 months ago

Fire would not be a great idea, I think it would be likely to leave residue on the needle depending on the flame source

I think also we might have used straight ethanol but that felt wrong because there are a lot of weird tax/legal implications/students could have drank it/etc etc, but I think isopropyl might leave residue, idk

And thankfully not a concern with pre-sterilized needles.

my b I don't really inject things because I don't like needles and did not think to realize that they would come pre-sterilized and not also be part of a DIY thing. That's p. dumb of me u_u

[-] Black_Mald_Futures@hexbear.net 3 points 5 months ago* (last edited 5 months ago)

Boiling water limits it to 100c and it's possible for spore forming bacteria and other things to survive, which can be mitigated (idk about estrogen, I mean to like sterilize water, i imagine multiple boilings might affect the quality of the drug) by boiling multiple times and allowing it to cool in between (so those spores germinate, then die before replicating)

To really sterilize things you need high temps which require pressure i.e. an autoclave professionally or a pressure cooker for the home sterility enthusiast or high temperature mediums like oil would work i guess but i feel like there's probably reasons autoclaves and pressure cookers get used for stuff like lab sterilization procedures or growing magic mushrooms at home and tbh idk maybe i'm ignorant but 120C definitely sounds really low to sterilize things but i guess there's also levels of sterility and cleanliness needed so maybe it's fine with this estrogen production method. Idk dawgggg

[-] Chronicon@hexbear.net 4 points 5 months ago* (last edited 5 months ago)

the thing is there's not much point in autoclaving or otherwise sterilizing everything before you put the estrogen in because the powder itself is not going to be perfectly sterile (hence doing it after, cooking the entire finished vial at once) 120+C is a bit safer, but with the addition of benzyl alcohol I'm not extremely worried. I did consider getting a lab steam sterilizer (purpose built pressure cooker) but decided against it for at least the first batch. You can't go too much past 130C iirc because it starts to affect the estrogen. I appreciate the concern and it's a good PSA I suppose, but as much as possible any risks I've taken were done soberly and with awareness.

But yeah if anyone else is going to do this I guess I'd advise doing the oil or pressurized steam method not just boiling water. That wasn't really the point of my comment and I should have left it off. See my other comment for notes on needles.

[-] Black_Mald_Futures@hexbear.net 4 points 5 months ago

I appreciate the concern and it's a good PSA I suppose, but as much as possible any risks I've taken were done soberly and with awareness.

solidarity

with my cishet ignorance and your trans aware knowledge we've spread info to the universe, good job us m i rite

[-] Chronicon@hexbear.net 4 points 5 months ago

stalin-heart

The other thing I remembered was that the heat may make the benzyl alcohol more effective against spores:

But yeah, higher temp better really (and if you can't do that, then boil longer, 1hr or 2 separate intervals of 30m), I don't mean to justify my laziness too much. This is also my first go at injecting things, but between friends who've gotten HRT from their doctors and reading on the internet I think I'm doing okay

[-] Black_Mald_Futures@hexbear.net 4 points 5 months ago

The other thing I remembered was that the heat may make the benzyl alcohol more effective against spores:

oh cool yeah that works then. I don't know anything about benzyl alcohol but if it's killin' them spores at a lower temp and also injection safe then that's p. cool

higher temp better really (and if you can't do that, then boil longer, 1hr or 2 separate intervals of 30m),

Yeah higher temp always kills things better but the important thing is if limited to boiling temps to use multiple boiling intervals. I think we re-boiled at shorter intervals in my micro class but 30 minutes or more sounds better imo, let them spores think they're safe then GETTEM hero-megalomania lol

This is also my first go at injecting things, but between friends who've gotten HRT from their doctors and reading on the internet I think I'm doing okay

well keep up the good work and keep doin' okay fidel-salute

[-] Mokey@hexbear.net 11 points 5 months ago

Lets go

[-] nathanfieldertulpa@hexbear.net 8 points 5 months ago

cat-trans

[-] Luna@hexbear.net 7 points 5 months ago

Congrats!

[-] magi@hexbear.net 6 points 5 months ago

Congratulations aubrey-happy

[-] GenderIsOpSec@hexbear.net 5 points 5 months ago

Hell yeah, comrade! bridget-vibe

[-] MusicOwl@hexbear.net 4 points 5 months ago

trans-ferret

[-] ComradeLeonie@hexbear.net 4 points 5 months ago

11mg EEn every 14 days is a hell of a dose. I take 3mg every 7 days and am at around 200 pg/ml E2.

[-] ZoomeristLeninist@hexbear.net 4 points 5 months ago* (last edited 5 months ago)

the half life of EEn is 6-7 days. this calculator shows ur dose giving a trough of 170 pg/mL and peak of 190 pg/mL so i assume it’s a decently accurate calc. when i plug in my dose it shows a trough of 210 and a peak of 430. this is high but im trying to suppress my T with monotherapy. once my T is low ill lower my dose to give me E2 of 150-320 (prob 8 mg). thanks for looking out for me! ill be keeping up with bloodwork

this post was submitted on 01 Jul 2024

141 points (98.6% liked)

traaaaaaannnnnnnnnns

992 readers

222 users here now

Welcome to /c/traaaaaaannnnnnnnnns, an anti-capitalist meme community for transgender and gender diverse people.

Please follow the Hexbear Code of Conduct
Selfies are not permitted for the personal safety of users.
No personal identifying information may be posted or commented.
Stay on topic (trans/gender stuff).
Bring a trans friend!
Any image post that gets 200 upvotes with "banner" or "rule 6" in the title becomes the new banner.
Posts about dysphoria/trauma/transphobia should be NSFW tagged for community health purposes.
When made outside of NSFW tagged posts, comments about dysphoria/traumatic/transphobic material should be spoiler tagged.
Arguing in favor of transmedicalism is unacceptable. This is an inclusive and intersectional community.
While this is mostly a meme community, we allow most trans related posts as we grow the trans community on the fediverse.